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On the Complexity of Human Neuroanatomy at the Millimeter Morphome Scale: Developing Codes and Characterizing Entropy Indexed to Spatial Scale

Overview of attention for article published in Frontiers in Neuroscience, October 2017
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Title
On the Complexity of Human Neuroanatomy at the Millimeter Morphome Scale: Developing Codes and Characterizing Entropy Indexed to Spatial Scale
Published in
Frontiers in Neuroscience, October 2017
DOI 10.3389/fnins.2017.00577
Pubmed ID
Authors

Daniel J. Tward, Michael I. Miller

Abstract

In this work we devise a strategy for discrete coding of anatomical form as described by a Bayesian prior model, quantifying the entropy of this representation as a function of code rate (number of bits), and its relationship geometric accuracy at clinically relevant scales. We study the shape of subcortical gray matter structures in the human brain through diffeomorphic transformations that relate them to a template, using data from the Alzheimer's Disease Neuroimaging Initiative to train a multivariate Gaussian prior model. We find that the at 1 mm accuracy all subcortical structures can be described with less than 35 bits, and at 1.5 mm error all structures can be described with less than 12 bits. This work represents a first step towards quantifying the amount of information ordering a neuroimaging study can provide about disease status.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 40%
Researcher 2 40%
Lecturer 1 20%
Readers by discipline Count As %
Engineering 2 40%
Chemical Engineering 1 20%
Medicine and Dentistry 1 20%
Social Sciences 1 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2017.
All research outputs
#16,725,651
of 25,382,440 outputs
Outputs from Frontiers in Neuroscience
#7,427
of 11,542 outputs
Outputs of similar age
#203,878
of 336,554 outputs
Outputs of similar age from Frontiers in Neuroscience
#149
of 184 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,554 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 184 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.