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Attention Score in Context
| Title |
SSRI and Motor Recovery in Stroke: Reestablishment of Inhibitory Neural Network Tonus
|
|---|---|
| Published in |
Frontiers in Neuroscience, November 2017
|
| DOI | 10.3389/fnins.2017.00637 |
| Pubmed ID | |
| Authors |
Camila B. Pinto, Faddi G. Saleh Velez, Fernanda Lopes, Polyana V. de Toledo Piza, Laura Dipietro, Qing M. Wang, Nicole L. Mazwi, Erica C. Camargo, Randie Black-Schaffer, Felipe Fregni |
| Abstract |
Selective serotonin reuptake inhibitors (SSRIs) are currently widely used in the field of the neuromodulation not only because of their anti-depressive effects but also due to their ability to promote plasticity and enhance motor recovery in patients with stroke. Recent studies showed that fluoxetine promotes motor recovery after stroke through its effects on the serotonergic system enhancing motor outputs and facilitating long term potentiation, key factors in motor neural plasticity. However, little is known in regards of the exact mechanisms underlying these effects and several aspects of it remain poorly understood. In this manuscript, we discuss evidence supporting the hypothesis that SSRIs, and in particular fluoxetine, modulate inhibitory pathways, and that this modulation enhances reorganization and reestablishment of excitatory-inhibitory control; these effects play a key role in learning induced plasticity in neural circuits involved in the promotion of motor recovery after stroke. This discussion aims to provide important insights and rationale for the development of novel strategies for stroke motor rehabilitation. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 14% |
| China | 1 | 14% |
| Iraq | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Practitioners (doctors, other healthcare professionals) | 2 | 29% |
| Scientists | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 86 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 17 | 20% |
| Researcher | 10 | 12% |
| Student > Ph. D. Student | 8 | 9% |
| Student > Master | 8 | 9% |
| Student > Postgraduate | 6 | 7% |
| Other | 19 | 22% |
| Unknown | 18 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 19 | 22% |
| Medicine and Dentistry | 18 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 7% |
| Psychology | 6 | 7% |
| Unspecified | 3 | 3% |
| Other | 11 | 13% |
| Unknown | 23 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2018.
All research outputs
#8,264,793
of 25,382,440 outputs
Outputs from Frontiers in Neuroscience
#5,239
of 11,542 outputs
Outputs of similar age
#118,669
of 318,891 outputs
Outputs of similar age from Frontiers in Neuroscience
#82
of 190 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,891 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 190 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.