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ER Dynamics and Derangement in Neurological Diseases

Overview of attention for article published in Frontiers in Neuroscience, February 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (61st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

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7 X users

Citations

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16 Dimensions

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63 Mendeley
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Title
ER Dynamics and Derangement in Neurological Diseases
Published in
Frontiers in Neuroscience, February 2018
DOI 10.3389/fnins.2018.00091
Pubmed ID
Authors

Tomoyuki Yamanaka, Nobuyuki Nukina

Abstract

The endoplasmic reticulum (ER) is a morphologically dynamic organelle containing different membrane subdomains with distinct cellular functions. Numerous observations have revealed that ER stress response induced by disturbed ER homeostasis is linked to various neurological/neurodegenerative disorders. In contrast, recent findings unveil that ER structural derangements are linked to the progression of several neurological diseases. The derangements involve two distinct, and likely opposing pathways. One is dysfunction of ER dynamics machinery, leading to disruption of ER network organization. Another one is facilitation of pre-existing machinery, leading to generation of markedly-orderedde novomembranous structure. Restoring the ER network can be the effective way toward the cure of ER-deranged neurological disorders.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 27%
Student > Bachelor 10 16%
Researcher 6 10%
Student > Master 6 10%
Student > Doctoral Student 2 3%
Other 7 11%
Unknown 15 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 18 29%
Agricultural and Biological Sciences 8 13%
Neuroscience 7 11%
Medicine and Dentistry 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 7 11%
Unknown 18 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 March 2018.
All research outputs
#7,963,683
of 25,382,440 outputs
Outputs from Frontiers in Neuroscience
#5,072
of 11,542 outputs
Outputs of similar age
#129,791
of 344,345 outputs
Outputs of similar age from Frontiers in Neuroscience
#110
of 232 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,345 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 232 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.