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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Involvement of Innate and Adaptive Immune Systems Alterations in the Pathophysiology and Treatment of Depression
|
|---|---|
| Published in |
Frontiers in Neuroscience, August 2018
|
| DOI | 10.3389/fnins.2018.00547 |
| Pubmed ID | |
| Authors |
Eva M. Medina-Rodriguez, Jeffrey A. Lowell, Ryan J. Worthen, Shariful A. Syed, Eléonore Beurel |
| Abstract |
Major depressive disorder (MDD) is a prevalent and debilitating disorder, often fatal. Treatment options are few and often do not provide immediate relief to the patients. The increasing involvement of inflammation in the pathology of MDD has provided new potential therapeutic avenues. Cytokine levels are elevated in the blood and cerebrospinal fluid of MDD patients whereas immune cells often exhibit an immunosuppressed phenotype in MDD patients. Blocking cytokine actions in patients exhibiting MDD show some antidepressant efficacy. However, the role of cytokines, and the immune response in MDD patients remain to be determined. We reviewed here the roles of the innate and adaptive immune systems in MDD, as well as potential mechanisms whereby the immune response might be regulated in MDD. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 75% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 111 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 21 | 19% |
| Student > Ph. D. Student | 19 | 17% |
| Student > Bachelor | 11 | 10% |
| Student > Master | 11 | 10% |
| Professor > Associate Professor | 3 | 3% |
| Other | 9 | 8% |
| Unknown | 37 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 16 | 14% |
| Medicine and Dentistry | 12 | 11% |
| Psychology | 9 | 8% |
| Agricultural and Biological Sciences | 7 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 6% |
| Other | 14 | 13% |
| Unknown | 46 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2020.
All research outputs
#15,745,807
of 25,385,509 outputs
Outputs from Frontiers in Neuroscience
#6,691
of 11,542 outputs
Outputs of similar age
#190,389
of 341,403 outputs
Outputs of similar age from Frontiers in Neuroscience
#152
of 238 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,403 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 238 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.