Title |
Stress in Regulation of GABA Amygdala System and Relevance to Neuropsychiatric Diseases
|
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Published in |
Frontiers in Neuroscience, August 2018
|
DOI | 10.3389/fnins.2018.00562 |
Pubmed ID | |
Authors |
Fan Jie, Guanghao Yin, Wei Yang, Modi Yang, Shuohui Gao, Jiayin Lv, Bingjin Li |
Abstract |
The amygdala is an almond-shaped nucleus located deep and medially within the temporal lobe and is thought to play a crucial role in the regulation of emotional processes. GABAergic neurotransmission inhibits the amygdala and prevents us from generating inappropriate emotional and behavioral responses. Stress may cause the reduction of the GABAergic interneuronal network and the development of neuropsychological diseases. In this review, we summarize the recent evidence investigating the possible mechanisms underlying GABAergic control of the amygdala and its interaction with acute and chronic stress. Taken together, this study may contribute to future progress in finding new approaches to reverse the attenuation of GABAergic neurotransmission induced by stress in the amygdala. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 30% |
Iraq | 1 | 10% |
Germany | 1 | 10% |
Canada | 1 | 10% |
Switzerland | 1 | 10% |
Unknown | 3 | 30% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Scientists | 1 | 10% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 173 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 31 | 18% |
Student > Master | 22 | 13% |
Researcher | 18 | 10% |
Student > Ph. D. Student | 16 | 9% |
Student > Doctoral Student | 7 | 4% |
Other | 18 | 10% |
Unknown | 61 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 30 | 17% |
Biochemistry, Genetics and Molecular Biology | 16 | 9% |
Nursing and Health Professions | 12 | 7% |
Medicine and Dentistry | 12 | 7% |
Agricultural and Biological Sciences | 9 | 5% |
Other | 30 | 17% |
Unknown | 64 | 37% |