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Mendeley readers
Attention Score in Context
| Title |
Emerging Roles of Glycogen Synthase Kinase 3 in the Treatment of Brain Tumors
|
|---|---|
| Published in |
Frontiers in Molecular Neuroscience, January 2011
|
| DOI | 10.3389/fnmol.2011.00047 |
| Pubmed ID | |
| Authors |
Caroline N. Mills, Somaira Nowsheen, James A. Bonner, Eddy S. Yang |
| Abstract |
The constitutively active protein glycogen synthase kinase 3 (GSK3), a serine/threonine kinase, acts paradoxically as a tumor suppressor in some cancers while potentiates growth in others. Deciphering what governs its actions is vital for understanding many pathological conditions, including brain cancer. What are seemingly disparate roles of GSK3 stems from the complex regulation of many cellular functions by GSK3. This review focuses on the regulation of GSK3, its role in survival, apoptosis and DNA damage, and finally its potential therapeutic impact in brain cancer. A thorough understanding of this versatile protein is critical for improving the outcome of various diseases, especially cancer. |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 55 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 18% |
| Student > Bachelor | 10 | 18% |
| Student > Master | 8 | 14% |
| Student > Ph. D. Student | 5 | 9% |
| Professor > Associate Professor | 5 | 9% |
| Other | 7 | 13% |
| Unknown | 11 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 16 | 29% |
| Biochemistry, Genetics and Molecular Biology | 13 | 23% |
| Medicine and Dentistry | 8 | 14% |
| Chemistry | 4 | 7% |
| Neuroscience | 3 | 5% |
| Other | 1 | 2% |
| Unknown | 11 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2019.
All research outputs
#7,453,126
of 22,785,242 outputs
Outputs from Frontiers in Molecular Neuroscience
#1,039
of 2,863 outputs
Outputs of similar age
#54,382
of 180,646 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#7
of 27 outputs
Altmetric has tracked 22,785,242 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,863 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,646 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.