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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Stress and addiction: contribution of the corticotropin releasing factor (CRF) system in neuroplasticity
|
|---|---|
| Published in |
Frontiers in Molecular Neuroscience, January 2012
|
| DOI | 10.3389/fnmol.2012.00091 |
| Pubmed ID | |
| Authors |
Carolina L. Haass-Koffler, Selena E. Bartlett |
| Abstract |
Corticotropin releasing factor (CRF) has been shown to induce various behavioral changes related to adaptation to stress. Dysregulation of the CRF system at any point can lead to a variety of psychiatric disorders, including substance use disorders (SUDs). CRF has been associated with stress-induced drug reinforcement. Extensive literature has identified CRF to play an important role in the molecular mechanisms that lead to an increase in susceptibility that precipitates relapse to SUDs. The CRF system has a heterogeneous role in SUDs. It enhances the acute effects of drugs of abuse and is also responsible for the potentiation of drug-induced neuroplasticity evoked during the withdrawal period. We present in this review the brain regions and circuitries where CRF is expressed and may participate in stress-induced drug abuse. Finally, we attempt to evaluate the role of modulating the CRF system as a possible therapeutic strategy for treating the dysregulation of emotional behaviors that result from the acute positive reinforcement of substances of abuse as well as the negative reinforcement produced by withdrawal. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 50% |
| Switzerland | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 92 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 23% |
| Student > Master | 13 | 14% |
| Researcher | 12 | 13% |
| Student > Bachelor | 8 | 9% |
| Student > Doctoral Student | 7 | 7% |
| Other | 11 | 12% |
| Unknown | 21 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 21 | 22% |
| Agricultural and Biological Sciences | 19 | 20% |
| Medicine and Dentistry | 12 | 13% |
| Psychology | 8 | 9% |
| Biochemistry, Genetics and Molecular Biology | 2 | 2% |
| Other | 7 | 7% |
| Unknown | 25 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2013.
All research outputs
#13,367,517
of 22,678,224 outputs
Outputs from Frontiers in Molecular Neuroscience
#1,303
of 2,826 outputs
Outputs of similar age
#146,666
of 244,088 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#21
of 48 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,826 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,088 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.