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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Optical modulation of neurotransmission using calcium photocurrents through the ion channel LiGluR
|
|---|---|
| Published in |
Frontiers in Molecular Neuroscience, January 2013
|
| DOI | 10.3389/fnmol.2013.00003 |
| Pubmed ID | |
| Authors |
Mercè Izquierdo-Serra, Dirk Trauner, Artur Llobet, Pau Gorostiza |
| Abstract |
A wide range of light-activated molecules (photoswitches and phototriggers) have been used to the study of computational properties of an isolated neuron by acting pre and postsynaptically. However, new tools are being pursued to elicit a presynaptic calcium influx that triggers the release of neurotransmitters, most of them based in calcium-permeable Channelrhodopsin-2 mutants. Here we describe a method to control exocytosis of synaptic vesicles through the use of a light-gated glutamate receptor (LiGluR), which has recently been demonstrated that supports secretion by means of calcium influx in chromaffin cells. Expression of LiGluR in hippocampal neurons enables reversible control of neurotransmission with light, and allows modulating the firing rate of the postsynaptic neuron with the wavelength of illumination. This method may be useful for the determination of the complex transfer function of individual synapses. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 20% |
| Switzerland | 1 | 20% |
| Japan | 1 | 20% |
| United States | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Scientists | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Canada | 1 | 2% |
| Switzerland | 1 | 2% |
| Unknown | 44 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 30% |
| Student > Master | 8 | 17% |
| Researcher | 7 | 15% |
| Professor > Associate Professor | 4 | 9% |
| Professor | 3 | 6% |
| Other | 8 | 17% |
| Unknown | 3 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 22 | 47% |
| Chemistry | 8 | 17% |
| Neuroscience | 7 | 15% |
| Biochemistry, Genetics and Molecular Biology | 4 | 9% |
| Engineering | 3 | 6% |
| Other | 1 | 2% |
| Unknown | 2 | 4% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2013.
All research outputs
#13,148,117
of 22,701,287 outputs
Outputs from Frontiers in Molecular Neuroscience
#1,222
of 2,833 outputs
Outputs of similar age
#155,731
of 280,698 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#15
of 39 outputs
Altmetric has tracked 22,701,287 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,833 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,698 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.