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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Long-term optical stimulation of channelrhodopsin-expressing neurons to study network plasticity
|
|---|---|
| Published in |
Frontiers in Molecular Neuroscience, January 2013
|
| DOI | 10.3389/fnmol.2013.00022 |
| Pubmed ID | |
| Authors |
Gabriele Lignani, Enrico Ferrea, Francesco Difato, Jessica Amarù, Eleonora Ferroni, Eleonora Lugarà, Stefano Espinoza, Raul R. Gainetdinov, Pietro Baldelli, Fabio Benfenati |
| Abstract |
Neuronal plasticity produces changes in excitability, synaptic transmission, and network architecture in response to external stimuli. Network adaptation to environmental conditions takes place in time scales ranging from few seconds to days, and modulates the entire network dynamics. To study the network response to defined long-term experimental protocols, we setup a system that combines optical and electrophysiological tools embedded in a cell incubator. Primary hippocampal neurons transduced with lentiviruses expressing channelrhodopsin-2/H134R were subjected to various photostimulation protocols in a time window in the order of days. To monitor the effects of light-induced gating of network activity, stimulated transduced neurons were simultaneously recorded using multi-electrode arrays (MEAs). The developed experimental model allows discerning short-term, long-lasting, and adaptive plasticity responses of the same neuronal network to distinct stimulation frequencies applied over different temporal windows. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 3% |
| Germany | 2 | 1% |
| Portugal | 2 | 1% |
| Belgium | 1 | <1% |
| Hong Kong | 1 | <1% |
| Unknown | 174 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 54 | 29% |
| Researcher | 47 | 25% |
| Student > Master | 23 | 12% |
| Student > Bachelor | 19 | 10% |
| Other | 6 | 3% |
| Other | 18 | 10% |
| Unknown | 18 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 56 | 30% |
| Neuroscience | 40 | 22% |
| Engineering | 21 | 11% |
| Medicine and Dentistry | 13 | 7% |
| Physics and Astronomy | 8 | 4% |
| Other | 18 | 10% |
| Unknown | 29 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2013.
All research outputs
#17,693,152
of 22,716,996 outputs
Outputs from Frontiers in Molecular Neuroscience
#2,036
of 2,841 outputs
Outputs of similar age
#210,190
of 280,757 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#23
of 39 outputs
Altmetric has tracked 22,716,996 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,841 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,757 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.