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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Biology of adeno-associated viral vectors in the central nervous system
|
|---|---|
| Published in |
Frontiers in Molecular Neuroscience, September 2014
|
| DOI | 10.3389/fnmol.2014.00076 |
| Pubmed ID | |
| Authors |
Giridhar Murlidharan, Richard J. Samulski, Aravind Asokan |
| Abstract |
Gene therapy is a promising approach for treating a spectrum of neurological and neurodegenerative disorders by delivering corrective genes to the central nervous system (CNS). In particular, adeno-associated viruses (AAVs) have emerged as promising tools for clinical gene transfer in a broad range of genetic disorders with neurological manifestations. In the current review, we have attempted to bridge our understanding of the biology of different AAV strains with their transduction profiles, cellular tropisms, and transport mechanisms within the CNS. Continued efforts to dissect AAV-host interactions within the brain are likely to aid in the development of improved vectors for CNS-directed gene transfer applications in the clinic. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 444 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 1% |
| Germany | 3 | <1% |
| France | 3 | <1% |
| Switzerland | 1 | <1% |
| United Kingdom | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 430 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 107 | 24% |
| Researcher | 72 | 16% |
| Student > Bachelor | 66 | 15% |
| Student > Master | 58 | 13% |
| Student > Doctoral Student | 22 | 5% |
| Other | 51 | 11% |
| Unknown | 68 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 124 | 28% |
| Neuroscience | 102 | 23% |
| Biochemistry, Genetics and Molecular Biology | 65 | 15% |
| Medicine and Dentistry | 21 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 3% |
| Other | 43 | 10% |
| Unknown | 77 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2023.
All research outputs
#2,712,177
of 23,910,532 outputs
Outputs from Frontiers in Molecular Neuroscience
#295
of 3,080 outputs
Outputs of similar age
#30,002
of 253,309 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#1
of 7 outputs
Altmetric has tracked 23,910,532 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,080 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,309 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them