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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Molecular Mechanisms Involved in Schwann Cell Plasticity
|
|---|---|
| Published in |
Frontiers in Molecular Neuroscience, February 2017
|
| DOI | 10.3389/fnmol.2017.00038 |
| Pubmed ID | |
| Authors |
Angélique Boerboom, Valérie Dion, Alain Chariot, Rachelle Franzen |
| Abstract |
Schwann cell incredible plasticity is a hallmark of the utmost importance following nerve damage or in demyelinating neuropathies. After injury, Schwann cells undergo dedifferentiation before redifferentiating to promote nerve regeneration and complete functional recovery. This review updates and discusses the molecular mechanisms involved in the negative regulation of myelination as well as in the reprogramming of Schwann cells taking place early following nerve lesion to support repair. Significant advance has been made on signaling pathways and molecular components that regulate SC regenerative properties. These include for instance transcriptional regulators such as c-Jun or Notch, the MAPK and the Nrg1/ErbB2/3 pathways. This comprehensive overview ends with some therapeutical applications targeting factors that control Schwann cell plasticity and highlights the need to carefully modulate and balance this capacity to drive nerve repair. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 235 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 235 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 48 | 20% |
| Student > Bachelor | 30 | 13% |
| Researcher | 28 | 12% |
| Student > Master | 28 | 12% |
| Student > Doctoral Student | 15 | 6% |
| Other | 30 | 13% |
| Unknown | 56 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 48 | 20% |
| Neuroscience | 37 | 16% |
| Agricultural and Biological Sciences | 29 | 12% |
| Medicine and Dentistry | 27 | 11% |
| Engineering | 7 | 3% |
| Other | 20 | 9% |
| Unknown | 67 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2017.
All research outputs
#20,406,219
of 22,955,959 outputs
Outputs from Frontiers in Molecular Neuroscience
#2,484
of 2,898 outputs
Outputs of similar age
#269,902
of 309,446 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#83
of 98 outputs
Altmetric has tracked 22,955,959 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,898 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,446 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 98 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.