Title |
Autoimmune Neurological Conditions Associated With Zika Virus Infection
|
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Published in |
Frontiers in Molecular Neuroscience, April 2018
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DOI | 10.3389/fnmol.2018.00116 |
Pubmed ID | |
Authors |
Yeny Acosta-Ampudia, Diana M. Monsalve, Luis F. Castillo-Medina, Yhojan Rodríguez, Yovana Pacheco, Susan Halstead, Hugh J. Willison, Juan-Manuel Anaya, Carolina Ramírez-Santana |
Abstract |
Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. Aedes mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, and body fluids. ZIKV infection is often asymptomatic and those with symptoms present minor illness after 3 to 12 days of incubation, characterized by a mild and self-limiting disease with low-grade fever, conjunctivitis, widespread pruritic maculopapular rash, arthralgia and myalgia. ZIKV has been linked to a number of central and peripheral nervous system injuries such as Guillain-Barré syndrome (GBS), transverse myelitis (TM), meningoencephalitis, ophthalmological manifestations, and other neurological complications. Nevertheless, mechanisms of host-pathogen neuro-immune interactions remain incompletely elucidated. This review provides a critical discussion about the possible mechanisms underlying the development of autoimmune neurological conditions associated with Zika virus infection. |
X Demographics
Geographical breakdown
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United Kingdom | 1 | 25% |
Colombia | 1 | 25% |
Switzerland | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 132 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 28 | 21% |
Student > Master | 16 | 12% |
Student > Ph. D. Student | 14 | 11% |
Researcher | 9 | 7% |
Student > Doctoral Student | 9 | 7% |
Other | 17 | 13% |
Unknown | 39 | 30% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 25 | 19% |
Agricultural and Biological Sciences | 16 | 12% |
Immunology and Microbiology | 14 | 11% |
Biochemistry, Genetics and Molecular Biology | 13 | 10% |
Neuroscience | 6 | 5% |
Other | 15 | 11% |
Unknown | 43 | 33% |