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Leptin regulation of neuronal morphology and hippocampal synaptic function

Overview of attention for article published in Frontiers in Synaptic Neuroscience, January 2013
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Title
Leptin regulation of neuronal morphology and hippocampal synaptic function
Published in
Frontiers in Synaptic Neuroscience, January 2013
DOI 10.3389/fnsyn.2013.00003
Pubmed ID
Authors

Jenni Harvey, Harvey, Jenni

Abstract

The central actions of the hormone leptin in regulating energy homeostasis via the hypothalamus are well documented. However, evidence is growing that this hormone can also modify the structure and function of synapses throughout the CNS. The hippocampus is a region of the forebrain that plays a crucial role in associative learning and memory and is an area also highly vulnerable to neurodegenerative processes. Recent studies indicate that leptin is a potential cognitive enhancer as it modulates the cellular processes underlying hippocampal-dependent learning and memory including dendritic morphology, glutamate receptor trafficking and activity-dependent synaptic plasticity. Here, we review the recent evidence implicating the hormone leptin as a key regulator of hippocampal synaptic function and discuss the role of leptin receptor-driven lipid signaling pathways involved in this process.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 3%
Japan 1 1%
Portugal 1 1%
Canada 1 1%
Unknown 62 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 19%
Student > Master 10 15%
Student > Bachelor 10 15%
Researcher 9 13%
Student > Doctoral Student 3 4%
Other 9 13%
Unknown 13 19%
Readers by discipline Count As %
Neuroscience 16 24%
Agricultural and Biological Sciences 11 16%
Medicine and Dentistry 10 15%
Biochemistry, Genetics and Molecular Biology 4 6%
Psychology 4 6%
Other 5 7%
Unknown 17 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2013.
All research outputs
#18,345,822
of 22,719,618 outputs
Outputs from Frontiers in Synaptic Neuroscience
#326
of 408 outputs
Outputs of similar age
#218,056
of 280,759 outputs
Outputs of similar age from Frontiers in Synaptic Neuroscience
#3
of 8 outputs
Altmetric has tracked 22,719,618 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 408 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,759 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.