You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Synaptic Vesicle Proteins and Active Zone Plasticity
|
|---|---|
| Published in |
Frontiers in Synaptic Neuroscience, April 2016
|
| DOI | 10.3389/fnsyn.2016.00008 |
| Pubmed ID | |
| Authors |
Robert J. Kittel, Manfred Heckmann |
| Abstract |
Neurotransmitter is released from synaptic vesicles at the highly specialized presynaptic active zone (AZ). The complex molecular architecture of AZs mediates the speed, precision and plasticity of synaptic transmission. Importantly, structural and functional properties of AZs vary significantly, even for a given connection. Thus, there appear to be distinct AZ states, which fundamentally influence neuronal communication by controlling the positioning and release of synaptic vesicles. Vice versa, recent evidence has revealed that synaptic vesicle components also modulate organizational states of the AZ. The protein-rich cytomatrix at the active zone (CAZ) provides a structural platform for molecular interactions guiding vesicle exocytosis. Studies in Drosophila have now demonstrated that the vesicle proteins Synaptotagmin-1 (Syt1) and Rab3 also regulate glutamate release by shaping differentiation of the CAZ ultrastructure. We review these unexpected findings and discuss mechanistic interpretations of the reciprocal relationship between synaptic vesicles and AZ states, which has heretofore received little attention. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 33% |
| Switzerland | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 3 | 2% |
| Portugal | 1 | <1% |
| Switzerland | 1 | <1% |
| Netherlands | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 131 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 35 | 25% |
| Researcher | 29 | 21% |
| Student > Master | 17 | 12% |
| Student > Bachelor | 12 | 9% |
| Professor > Associate Professor | 5 | 4% |
| Other | 15 | 11% |
| Unknown | 25 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 55 | 40% |
| Agricultural and Biological Sciences | 31 | 22% |
| Biochemistry, Genetics and Molecular Biology | 13 | 9% |
| Medicine and Dentistry | 4 | 3% |
| Computer Science | 1 | <1% |
| Other | 8 | 6% |
| Unknown | 26 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2016.
All research outputs
#15,330,390
of 23,577,654 outputs
Outputs from Frontiers in Synaptic Neuroscience
#272
of 428 outputs
Outputs of similar age
#172,278
of 300,756 outputs
Outputs of similar age from Frontiers in Synaptic Neuroscience
#5
of 9 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 428 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,756 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.