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Neuromodulation of the Feedforward Dentate Gyrus-CA3 Microcircuit

Overview of attention for article published in Frontiers in Synaptic Neuroscience, October 2016
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Title
Neuromodulation of the Feedforward Dentate Gyrus-CA3 Microcircuit
Published in
Frontiers in Synaptic Neuroscience, October 2016
DOI 10.3389/fnsyn.2016.00032
Pubmed ID
Authors

Luke Y. Prince, Travis J. Bacon, Cezar M. Tigaret, Jack R. Mellor

Abstract

The feedforward dentate gyrus-CA3 microcircuit in the hippocampus is thought to activate ensembles of CA3 pyramidal cells and interneurons to encode and retrieve episodic memories. The creation of these CA3 ensembles depends on neuromodulatory input and synaptic plasticity within this microcircuit. Here we review the mechanisms by which the neuromodulators aceylcholine, noradrenaline, dopamine, and serotonin reconfigure this microcircuit and thereby infer the net effect of these modulators on the processes of episodic memory encoding and retrieval.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 103 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 35%
Student > Bachelor 12 12%
Researcher 11 11%
Student > Master 11 11%
Student > Doctoral Student 7 7%
Other 12 12%
Unknown 15 14%
Readers by discipline Count As %
Neuroscience 37 36%
Agricultural and Biological Sciences 22 21%
Medicine and Dentistry 7 7%
Biochemistry, Genetics and Molecular Biology 5 5%
Unspecified 4 4%
Other 11 11%
Unknown 18 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2016.
All research outputs
#14,864,294
of 22,893,031 outputs
Outputs from Frontiers in Synaptic Neuroscience
#261
of 414 outputs
Outputs of similar age
#189,286
of 315,552 outputs
Outputs of similar age from Frontiers in Synaptic Neuroscience
#4
of 7 outputs
Altmetric has tracked 22,893,031 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 414 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,552 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.