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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Can the Lateral Habenula Crack the Serotonin Code?
|
|---|---|
| Published in |
Frontiers in Synaptic Neuroscience, October 2016
|
| DOI | 10.3389/fnsyn.2016.00034 |
| Pubmed ID | |
| Authors |
Anna Tchenio, Kristina Valentinova, Manuel Mameli |
| Abstract |
The lateral habenula (LHb) and the serotonergic system both contribute to motivational states by encoding rewarding and aversive signals. Converging evidence suggests that perturbation of these systems is critical for the pathophysiology of mood disorders. Anatomical and functional studies indicate that the serotonergic system and the LHb are interconnected in a forward-feedback loop. However, how serotonin release modifies the synaptic and cellular properties of LHb neurons and whether this has any behavioral repercussions remain poorly investigated. In this review article, we discuss insights gained from rodents and humans regarding the implications of the serotonin system and the LHb in aversion encoding and related disorders. We then describe the type, properties and pharmacology of serotonergic receptors expressed throughout the LHb. Finally, we discuss physiological data reporting how serotonergic signaling modifies synaptic transmission and neuronal activity within the LHb. Altogether, we combine a mechanistic- and circuit-level knowledge to provide an overview on how the LHb integrates serotonergic signals, a process potentially contributing to LHb-dependent encoding of valenced external stimuli. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 6% |
| Unknown | 50 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 23% |
| Researcher | 9 | 17% |
| Student > Bachelor | 6 | 11% |
| Student > Doctoral Student | 5 | 9% |
| Unspecified | 3 | 6% |
| Other | 8 | 15% |
| Unknown | 10 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 22 | 42% |
| Unspecified | 3 | 6% |
| Medicine and Dentistry | 3 | 6% |
| Agricultural and Biological Sciences | 3 | 6% |
| Psychology | 3 | 6% |
| Other | 8 | 15% |
| Unknown | 11 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 April 2022.
All research outputs
#19,921,793
of 25,352,304 outputs
Outputs from Frontiers in Synaptic Neuroscience
#329
of 441 outputs
Outputs of similar age
#233,339
of 321,763 outputs
Outputs of similar age from Frontiers in Synaptic Neuroscience
#5
of 6 outputs
Altmetric has tracked 25,352,304 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 441 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,763 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.