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Extracellular Glutamate: Functional Compartments Operate in Different Concentration Ranges

Overview of attention for article published in Frontiers in Systems Neuroscience, January 2011
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Title
Extracellular Glutamate: Functional Compartments Operate in Different Concentration Ranges
Published in
Frontiers in Systems Neuroscience, January 2011
DOI 10.3389/fnsys.2011.00094
Pubmed ID
Authors

Khaled Moussawi, Arthur Riegel, Satish Nair, Peter W. Kalivas

Abstract

Extracellular glutamate of glial origin modulates glial and neuronal glutamate release and synaptic plasticity. Estimates of the tonic basal concentration of extracellular glutamate range over three orders of magnitude (0.02-20 μM) depending on the technology employed to make the measurement. Based upon binding constants for glutamate receptors and transporters, this range of concentrations translates into distinct physiological and pathophysiological roles for extracellular glutamate. Here we speculate that the difference in glutamate measurements can be explained if there is patterned membrane surface expression of glutamate release and transporter sites creating extracellular subcompartments that vary in glutamate concentration and are preferentially sampled by different technologies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 188 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Australia 1 <1%
Brazil 1 <1%
South Africa 1 <1%
Canada 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 181 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 51 27%
Researcher 25 13%
Student > Master 22 12%
Student > Bachelor 15 8%
Student > Doctoral Student 10 5%
Other 28 15%
Unknown 37 20%
Readers by discipline Count As %
Neuroscience 50 27%
Agricultural and Biological Sciences 44 23%
Medicine and Dentistry 11 6%
Biochemistry, Genetics and Molecular Biology 11 6%
Chemistry 10 5%
Other 20 11%
Unknown 42 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2012.
All research outputs
#17,655,049
of 22,662,201 outputs
Outputs from Frontiers in Systems Neuroscience
#1,053
of 1,338 outputs
Outputs of similar age
#158,502
of 180,278 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#31
of 40 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,338 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,278 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.