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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cerebral Low-Molecular Metabolites Influenced by Intestinal Microbiota: A Pilot Study
|
|---|---|
| Published in |
Frontiers in Systems Neuroscience, January 2013
|
| DOI | 10.3389/fnsys.2013.00009 |
| Pubmed ID | |
| Authors |
Mitsuharu Matsumoto, Ryoko Kibe, Takushi Ooga, Yuji Aiba, Emiko Sawaki, Yasuhiro Koga, Yoshimi Benno |
| Abstract |
Recent studies suggest that intestinal microbiota influences gut-brain communication. In this study, we aimed to clarify the influence of intestinal microbiota on cerebral metabolism. We analyzed the cerebral metabolome of germ-free (GF) mice and Ex-GF mice, which were inoculated with suspension of feces obtained from specific pathogen-free mice, using capillary electrophoresis with time-of-flight mass spectrometry (CE-TOFMS). CE-TOFMS identified 196 metabolites from the cerebral metabolome in both GF and Ex-GF mice. The concentrations of 38 metabolites differed significantly (p < 0.05) between GF and Ex-GF mice. Approximately 10 of these metabolites are known to be involved in brain function, whilst the functions of the remainder are unclear. Furthermore, we observed a novel association between cerebral glycolytic metabolism and intestinal microbiota. Our work shows that cerebral metabolites are influenced by normal intestinal microbiota through the microbiota-gut-brain axis, and indicates that normal intestinal microbiota closely connected with brain health and disease, development, attenuation, learning, memory, and behavior. |
X Demographics
The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 5 | 24% |
| United States | 2 | 10% |
| China | 1 | 5% |
| United Kingdom | 1 | 5% |
| France | 1 | 5% |
| Korea, Democratic People's Republic of | 1 | 5% |
| Unknown | 10 | 48% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 71% |
| Practitioners (doctors, other healthcare professionals) | 3 | 14% |
| Scientists | 3 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 288 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| France | 1 | <1% |
| Italy | 1 | <1% |
| South Africa | 1 | <1% |
| Canada | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 280 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 48 | 17% |
| Student > Ph. D. Student | 43 | 15% |
| Student > Master | 43 | 15% |
| Student > Bachelor | 34 | 12% |
| Student > Doctoral Student | 22 | 8% |
| Other | 44 | 15% |
| Unknown | 54 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 72 | 25% |
| Biochemistry, Genetics and Molecular Biology | 35 | 12% |
| Medicine and Dentistry | 33 | 11% |
| Neuroscience | 29 | 10% |
| Immunology and Microbiology | 17 | 6% |
| Other | 42 | 15% |
| Unknown | 60 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2021.
All research outputs
#1,754,237
of 25,743,152 outputs
Outputs from Frontiers in Systems Neuroscience
#127
of 1,410 outputs
Outputs of similar age
#15,562
of 290,964 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#14
of 94 outputs
Altmetric has tracked 25,743,152 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,410 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,964 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 94 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.