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Valproate reopens critical-period learning of absolute pitch

Overview of attention for article published in Frontiers in Systems Neuroscience, January 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 1,410)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

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Title
Valproate reopens critical-period learning of absolute pitch
Published in
Frontiers in Systems Neuroscience, January 2013
DOI 10.3389/fnsys.2013.00102
Pubmed ID
Authors

Judit Gervain, Bradley W. Vines, Lawrence M. Chen, Rubo J. Seo, Takao K. Hensch, Janet F. Werker, Allan H. Young

Abstract

Absolute pitch, the ability to identify or produce the pitch of a sound without a reference point, has a critical period, i.e., it can only be acquired early in life. However, research has shown that histone-deacetylase inhibitors (HDAC inhibitors) enable adult mice to establish perceptual preferences that are otherwise impossible to acquire after youth. In humans, we found that adult men who took valproate (VPA) (a HDAC inhibitor) learned to identify pitch significantly better than those taking placebo-evidence that VPA facilitated critical-period learning in the adult human brain. Importantly, this result was not due to a general change in cognitive function, but rather a specific effect on a sensory task associated with a critical-period.

X Demographics

X Demographics

The data shown below were collected from the profiles of 367 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 12 22%
Canada 5 9%
United Kingdom 4 7%
France 2 4%
Brazil 2 4%
Germany 2 4%
Netherlands 2 4%
Japan 2 4%
Spain 2 4%
Other 4 7%
Unknown 17 31%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 91 169%
Researcher 77 143%
Student > Bachelor 46 85%
Student > Master 41 76%
Professor > Associate Professor 28 52%
Other 85 157%
Readers by discipline Count As %
Agricultural and Biological Sciences 91 169%
Psychology 87 161%
Neuroscience 54 100%
Medicine and Dentistry 44 81%
Biochemistry, Genetics and Molecular Biology 17 31%
Other 51 94%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 735. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2024.
All research outputs
#27,750
of 25,746,891 outputs
Outputs from Frontiers in Systems Neuroscience
#1
of 1,410 outputs
Outputs of similar age
#107
of 290,973 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#1
of 94 outputs
Altmetric has tracked 25,746,891 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,410 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,973 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 94 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.