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Propofol and sevoflurane induce distinct burst suppression patterns in rats

Overview of attention for article published in Frontiers in Systems Neuroscience, December 2014
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1 YouTube creator

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Title
Propofol and sevoflurane induce distinct burst suppression patterns in rats
Published in
Frontiers in Systems Neuroscience, December 2014
DOI 10.3389/fnsys.2014.00237
Pubmed ID
Authors

Jonathan D. Kenny, M. Brandon Westover, ShiNung Ching, Emery N. Brown, Ken Solt

Abstract

Burst suppression is an EEG pattern characterized by alternating periods of high-amplitude activity (bursts) and relatively low amplitude activity (suppressions). Burst suppression can arise from several different pathological conditions, as well as from general anesthesia. Here we review current algorithms that are used to quantify burst suppression, its various etiologies, and possible underlying mechanisms. We then review clinical applications of anesthetic-induced burst suppression. Finally, we report the results of our new study showing clear electrophysiological differences in burst suppression patterns induced by two common general anesthetics, sevoflurane and propofol. Our data suggest that the circuit mechanisms that generate burst suppression activity may differ among general anesthetics.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Italy 1 1%
Germany 1 1%
Brazil 1 1%
Unknown 92 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 24%
Researcher 17 18%
Student > Bachelor 8 8%
Student > Doctoral Student 7 7%
Student > Postgraduate 6 6%
Other 19 20%
Unknown 16 17%
Readers by discipline Count As %
Neuroscience 28 29%
Medicine and Dentistry 22 23%
Engineering 10 10%
Agricultural and Biological Sciences 9 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Other 6 6%
Unknown 18 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 April 2020.
All research outputs
#14,791,252
of 22,772,779 outputs
Outputs from Frontiers in Systems Neuroscience
#886
of 1,341 outputs
Outputs of similar age
#198,131
of 353,291 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#20
of 34 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,341 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,291 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.