Title |
Propofol and sevoflurane induce distinct burst suppression patterns in rats
|
---|---|
Published in |
Frontiers in Systems Neuroscience, December 2014
|
DOI | 10.3389/fnsys.2014.00237 |
Pubmed ID | |
Authors |
Jonathan D. Kenny, M. Brandon Westover, ShiNung Ching, Emery N. Brown, Ken Solt |
Abstract |
Burst suppression is an EEG pattern characterized by alternating periods of high-amplitude activity (bursts) and relatively low amplitude activity (suppressions). Burst suppression can arise from several different pathological conditions, as well as from general anesthesia. Here we review current algorithms that are used to quantify burst suppression, its various etiologies, and possible underlying mechanisms. We then review clinical applications of anesthetic-induced burst suppression. Finally, we report the results of our new study showing clear electrophysiological differences in burst suppression patterns induced by two common general anesthetics, sevoflurane and propofol. Our data suggest that the circuit mechanisms that generate burst suppression activity may differ among general anesthetics. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
Italy | 1 | 1% |
Germany | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 92 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 23 | 24% |
Researcher | 17 | 18% |
Student > Bachelor | 8 | 8% |
Student > Doctoral Student | 7 | 7% |
Student > Postgraduate | 6 | 6% |
Other | 19 | 20% |
Unknown | 16 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 28 | 29% |
Medicine and Dentistry | 22 | 23% |
Engineering | 10 | 10% |
Agricultural and Biological Sciences | 9 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
Other | 6 | 6% |
Unknown | 18 | 19% |