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Adult hippocampal neurogenesis and pattern separation in DG: a role for feedback inhibition in modulating sparseness to govern population-based coding

Overview of attention for article published in Frontiers in Systems Neuroscience, August 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

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1 blog
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4 X users

Citations

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50 Dimensions

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116 Mendeley
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Title
Adult hippocampal neurogenesis and pattern separation in DG: a role for feedback inhibition in modulating sparseness to govern population-based coding
Published in
Frontiers in Systems Neuroscience, August 2015
DOI 10.3389/fnsys.2015.00120
Pubmed ID
Authors

Kathleen McAvoy, Antoine Besnard, Amar Sahay

Abstract

The dentate gyrus (DG) of mammals harbors neural stem cells that generate new dentate granule cells (DGCs) throughout life. Behavioral studies using the contextual fear discrimination paradigm have found that selectively augmenting or blocking adult hippocampal neurogenesis enhances or impairs discrimination under conditions of high, but not low, interference suggestive of a role in pattern separation. Although contextual discrimination engages population-based coding mechanisms underlying pattern separation such as global remapping in the DG and CA3, how adult hippocampal neurogenesis modulates pattern separation in the DG is poorly understood. Here, we propose a role for adult-born DGCs in re-activation coupled modulation of sparseness through feed-back inhibition to govern global remapping in the DG.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Germany 1 <1%
France 1 <1%
Canada 1 <1%
Unknown 111 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 22%
Student > Master 20 17%
Student > Bachelor 19 16%
Researcher 10 9%
Student > Doctoral Student 8 7%
Other 11 9%
Unknown 22 19%
Readers by discipline Count As %
Neuroscience 45 39%
Agricultural and Biological Sciences 22 19%
Psychology 12 10%
Medicine and Dentistry 4 3%
Physics and Astronomy 2 2%
Other 6 5%
Unknown 25 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2017.
All research outputs
#3,845,484
of 25,789,020 outputs
Outputs from Frontiers in Systems Neuroscience
#345
of 1,410 outputs
Outputs of similar age
#47,491
of 278,401 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#4
of 34 outputs
Altmetric has tracked 25,789,020 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,410 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.8. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,401 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.