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fMRI investigation of response inhibition, emotion, impulsivity, and clinical high-risk behavior in adolescents

Overview of attention for article published in Frontiers in Systems Neuroscience, September 2015
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Title
fMRI investigation of response inhibition, emotion, impulsivity, and clinical high-risk behavior in adolescents
Published in
Frontiers in Systems Neuroscience, September 2015
DOI 10.3389/fnsys.2015.00124
Pubmed ID
Authors

Matthew R. G. Brown, James R. A. Benoit, Michal Juhás, Ericson Dametto, Tiffanie T. Tse, Marnie MacKay, Bhaskar Sen, Alan M. Carroll, Oleksandr Hodlevskyy, Peter H. Silverstone, Florin Dolcos, Serdar M. Dursun, Andrew J. Greenshaw

Abstract

High-risk behavior in adolescents is associated with injury, mental health problems, and poor outcomes in later life. Improved understanding of the neurobiology of high-risk behavior and impulsivity shows promise for informing clinical treatment and prevention as well as policy to better address high-risk behavior. We recruited 21 adolescents (age 14-17) with a wide range of high-risk behavior tendencies, including medically high-risk participants recruited from psychiatric clinics. Risk tendencies were assessed using the Adolescent Risk Behavior Screen (ARBS). ARBS risk scores correlated highly (0.78) with impulsivity scores from the Barratt Impulsivity scale (BIS). Participants underwent 4.7 Tesla functional magnetic resonance imaging (fMRI) while performing an emotional Go/NoGo task. This task presented an aversive or neutral distractor image simultaneously with each Go or NoGo stimulus. Risk behavior and impulsivity tendencies exhibited similar but not identical associations with fMRI activation patterns in prefrontal brain regions. We interpret these results as reflecting differences in response inhibition, emotional stimulus processing, and emotion regulation in relation to participant risk behavior tendencies and impulsivity levels. The results are consistent with high impulsivity playing an important role in determining high risk tendencies in this sample containing clinically high-risk adolescents.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 115 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 16%
Researcher 15 13%
Student > Bachelor 14 12%
Student > Master 10 9%
Student > Doctoral Student 6 5%
Other 17 15%
Unknown 35 30%
Readers by discipline Count As %
Psychology 34 29%
Neuroscience 13 11%
Medicine and Dentistry 12 10%
Engineering 4 3%
Nursing and Health Professions 4 3%
Other 9 8%
Unknown 40 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2015.
All research outputs
#14,431,072
of 23,577,654 outputs
Outputs from Frontiers in Systems Neuroscience
#804
of 1,363 outputs
Outputs of similar age
#139,002
of 275,900 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#22
of 38 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,363 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,900 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.