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Hippocampal-Prefrontal Interactions in Cognition, Behavior and Psychiatric Disease

Overview of attention for article published in Frontiers in Systems Neuroscience, January 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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Title
Hippocampal-Prefrontal Interactions in Cognition, Behavior and Psychiatric Disease
Published in
Frontiers in Systems Neuroscience, January 2016
DOI 10.3389/fnsys.2015.00190
Pubmed ID
Authors

Torfi Sigurdsson, Sevil Duvarci

Abstract

The hippocampus and prefrontal cortex (PFC) have long been known to play a central role in various behavioral and cognitive functions. More recently, electrophysiological and functional imaging studies have begun to examine how interactions between the two structures contribute to behavior during various tasks. At the same time, it has become clear that hippocampal-prefrontal interactions are disrupted in psychiatric disease and may contribute to their pathophysiology. These impairments have most frequently been observed in schizophrenia, a disease that has long been associated with hippocampal and prefrontal dysfunction. Studies in animal models of the illness have also begun to relate disruptions in hippocampal-prefrontal interactions to the various risk factors and pathophysiological mechanisms of the illness. The goal of this review is to summarize what is known about the role of hippocampal-prefrontal interactions in normal brain function and compare how these interactions are disrupted in schizophrenia patients and animal models of the disease. Outstanding questions for future research on the role of hippocampal-prefrontal interactions in both healthy brain function and disease states are also discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 515 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 <1%
Hungary 1 <1%
Switzerland 1 <1%
Chile 1 <1%
France 1 <1%
Bulgaria 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
Unknown 505 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 124 24%
Researcher 73 14%
Student > Bachelor 52 10%
Student > Master 51 10%
Student > Doctoral Student 33 6%
Other 62 12%
Unknown 120 23%
Readers by discipline Count As %
Neuroscience 176 34%
Agricultural and Biological Sciences 66 13%
Psychology 40 8%
Medicine and Dentistry 26 5%
Biochemistry, Genetics and Molecular Biology 20 4%
Other 46 9%
Unknown 141 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2017.
All research outputs
#4,435,204
of 22,836,570 outputs
Outputs from Frontiers in Systems Neuroscience
#405
of 1,344 outputs
Outputs of similar age
#79,716
of 396,749 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#14
of 49 outputs
Altmetric has tracked 22,836,570 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,344 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 396,749 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.