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Hippocampal Neurophysiologic Changes after Mild Traumatic Brain Injury and Potential Neuromodulation Treatment Approaches

Overview of attention for article published in Frontiers in Systems Neuroscience, February 2016
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Title
Hippocampal Neurophysiologic Changes after Mild Traumatic Brain Injury and Potential Neuromodulation Treatment Approaches
Published in
Frontiers in Systems Neuroscience, February 2016
DOI 10.3389/fnsys.2016.00008
Pubmed ID
Authors

Fady Girgis, Jonathan Pace, Jennifer Sweet, Jonathan P. Miller

Abstract

Traumatic brain injury (TBI) is the leading cause of death and disability in individuals below age 45, and five million Americans live with chronic disability as a result. Mild TBI (mTBI), defined as TBI in the absence of major imaging or histopathological defects, is responsible for a majority of cases. Despite the lack of overt morphological defects, victims of mTBI frequently suffer lasting cognitive deficits, memory difficulties, and behavioral disturbances. There is increasing evidence that cognitive and memory dysfunction is related to subtle physiological changes that occur in the hippocampus, and these impact both the phenotype of deficits observed and subsequent recovery. Therapeutic modulation of physiological activity by means of medications commonly used for other indications or brain stimulation may represent novel treatment approaches. This review summarizes the present body of knowledge regarding neurophysiologic changes that occur in the hippocampus after mTBI, as well as potential targets for therapeutic modulation of neurologic activity.

X Demographics

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 184 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 17%
Student > Bachelor 28 15%
Researcher 16 9%
Student > Doctoral Student 15 8%
Other 14 8%
Other 42 23%
Unknown 38 21%
Readers by discipline Count As %
Neuroscience 37 20%
Medicine and Dentistry 24 13%
Psychology 17 9%
Agricultural and Biological Sciences 16 9%
Biochemistry, Genetics and Molecular Biology 11 6%
Other 33 18%
Unknown 46 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 May 2019.
All research outputs
#14,247,377
of 22,844,985 outputs
Outputs from Frontiers in Systems Neuroscience
#839
of 1,344 outputs
Outputs of similar age
#210,495
of 400,364 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#24
of 40 outputs
Altmetric has tracked 22,844,985 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,344 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,364 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.