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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Zinc is an Antioxidant and Anti-Inflammatory Agent: Its Role in Human Health
|
|---|---|
| Published in |
Frontiers in Nutrition, September 2014
|
| DOI | 10.3389/fnut.2014.00014 |
| Pubmed ID | |
| Authors |
Ananda S. Prasad |
| Abstract |
Zinc supplementation trials in the elderly showed that the incidence of infections was decreased by approximately 66% in the zinc group. Zinc supplementation also decreased oxidative stress biomarkers and decreased inflammatory cytokines in the elderly. In our studies in the experimental model of zinc deficiency in humans, we showed that zinc deficiency per se increased the generation of IL-1β and its mRNA in human mononuclear cells following LPS stimulation. Zinc supplementation upregulated A20, a zinc transcription factor, which inhibited the activation of NF-κB, resulting in decreased generation of inflammatory cytokines. Oxidative stress and chronic inflammation are important contributing factors for several chronic diseases attributed to aging, such as atherosclerosis and related cardiac disorders, cancer, neurodegeneration, immunologic disorders and the aging process itself. Zinc is very effective in decreasing reactive oxygen species (ROS). In this review, the mechanism of zinc actions on oxidative stress and generation of inflammatory cytokines and its impact on health in humans will be presented. |
X Demographics
The data shown below were collected from the profiles of 46 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 11% |
| Spain | 3 | 7% |
| Japan | 2 | 4% |
| India | 2 | 4% |
| Ireland | 1 | 2% |
| Georgia | 1 | 2% |
| Switzerland | 1 | 2% |
| Unknown | 31 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 39 | 85% |
| Practitioners (doctors, other healthcare professionals) | 3 | 7% |
| Scientists | 2 | 4% |
| Science communicators (journalists, bloggers, editors) | 2 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 428 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Australia | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 425 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 65 | 15% |
| Student > Ph. D. Student | 55 | 13% |
| Student > Master | 50 | 12% |
| Student > Postgraduate | 33 | 8% |
| Researcher | 28 | 7% |
| Other | 72 | 17% |
| Unknown | 125 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 87 | 20% |
| Agricultural and Biological Sciences | 44 | 10% |
| Biochemistry, Genetics and Molecular Biology | 31 | 7% |
| Nursing and Health Professions | 29 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 23 | 5% |
| Other | 75 | 18% |
| Unknown | 139 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 102. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2024.
All research outputs
#420,419
of 25,660,026 outputs
Outputs from Frontiers in Nutrition
#203
of 6,956 outputs
Outputs of similar age
#3,806
of 249,207 outputs
Outputs of similar age from Frontiers in Nutrition
#1
of 7 outputs
Altmetric has tracked 25,660,026 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,956 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,207 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them