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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The L-Cell in Nutritional Sensing and the Regulation of Appetite
|
|---|---|
| Published in |
Frontiers in Nutrition, January 2015
|
| DOI | 10.3389/fnut.2015.00023 |
| Pubmed ID | |
| Authors |
Eleanor Spreckley, Kevin Graeme Murphy |
| Abstract |
The gastrointestinal (GI) tract senses the ingestion of food and responds by signaling to the brain to promote satiation and satiety. Representing an important part of the gut-brain axis, enteroendocrine L-cells secrete the anorectic peptide hormones glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) in response to the ingestion of food. The release of GLP-1 has multiple effects, including the secretion of insulin from pancreatic β-cells, decreased gastric emptying, and increased satiation. PYY also slows GI motility and reduces food intake. At least part of the gut-brain response seems to be due to direct sensing of macronutrients by L-cells, by mechanisms including specific nutrient-sensing receptors. Such receptors may represent possible pathways to target to decrease appetite and increase energy expenditure. Designing drugs or functional foods to exploit the machinery of these nutrient-sensing mechanisms may offer a potential approach for agents to treat obesity and metabolic disease. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 302 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | <1% |
| United States | 1 | <1% |
| Russia | 1 | <1% |
| Unknown | 298 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 51 | 17% |
| Student > Master | 42 | 14% |
| Researcher | 38 | 13% |
| Student > Bachelor | 31 | 10% |
| Student > Doctoral Student | 17 | 6% |
| Other | 52 | 17% |
| Unknown | 71 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 55 | 18% |
| Agricultural and Biological Sciences | 51 | 17% |
| Biochemistry, Genetics and Molecular Biology | 47 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 17 | 6% |
| Nursing and Health Professions | 9 | 3% |
| Other | 47 | 16% |
| Unknown | 76 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2023.
All research outputs
#14,414,020
of 23,549,388 outputs
Outputs from Frontiers in Nutrition
#2,130
of 5,178 outputs
Outputs of similar age
#185,412
of 356,560 outputs
Outputs of similar age from Frontiers in Nutrition
#12
of 17 outputs
Altmetric has tracked 23,549,388 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,178 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,560 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.