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Radiation-induced effects and the immune system in cancer

Overview of attention for article published in Frontiers in oncology, January 2012
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  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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3 X users

Citations

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Readers on

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153 Mendeley
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Title
Radiation-induced effects and the immune system in cancer
Published in
Frontiers in oncology, January 2012
DOI 10.3389/fonc.2012.00191
Pubmed ID
Authors

Punit Kaur, Alexzander Asea

Abstract

Chemotherapy and radiation therapy (RT) are standard therapeutic modalities for patients with cancers, and could induce various tumor cell death modalities, releasing tumor-derived antigens as well as danger signals that could either be captured for triggering anti-tumor immune response. Historic studies examining tissue and cellular responses to RT have predominantly focused on damage caused to proliferating malignant cells leading to their death. However, there is increasing evidence that RT also leads to significant alterations in the tumor microenvironment, particularly with respect to effects on immune cells and infiltrating tumors. This review will focus on immunologic consequences of RT and discuss the therapeutic reprogramming of immune responses in tumors and how it regulates efficacy and durability to RT.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Portugal 1 <1%
Italy 1 <1%
South Africa 1 <1%
Unknown 149 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 24%
Student > Master 25 16%
Researcher 23 15%
Student > Bachelor 13 8%
Student > Doctoral Student 7 5%
Other 17 11%
Unknown 31 20%
Readers by discipline Count As %
Medicine and Dentistry 34 22%
Agricultural and Biological Sciences 25 16%
Biochemistry, Genetics and Molecular Biology 20 13%
Immunology and Microbiology 11 7%
Physics and Astronomy 5 3%
Other 21 14%
Unknown 37 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2013.
All research outputs
#16,722,913
of 25,374,917 outputs
Outputs from Frontiers in oncology
#6,609
of 22,416 outputs
Outputs of similar age
#168,824
of 250,099 outputs
Outputs of similar age from Frontiers in oncology
#59
of 161 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,416 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,099 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 161 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.