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Hypothesis: is yeast a clock model to study the onset of humans aging phenotypes?

Overview of attention for article published in Frontiers in oncology, January 2012
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  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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Title
Hypothesis: is yeast a clock model to study the onset of humans aging phenotypes?
Published in
Frontiers in oncology, January 2012
DOI 10.3389/fonc.2012.00203
Pubmed ID
Authors

Cristina Mazzoni, Eleonora Mangiapelo, Vanessa Palermo, Claudio Falcone

Abstract

In this paper we report the growth and aging of yeast colonies derived from single cells isolated by micromanipulation and seeded one by one on separated plates to avoid growth interference by surrounding colonies. We named this procedure clonal life span, and it could represent a third way of studying aging together with the replicative life span and chronological life span. In this study we observed over time the formation of cell mass similar to the human "senile warts" (seborrheic keratoses), the skin lesions that often appear after 30 years of life and increase in number and size over the years. We observed that similar signs of aging appear in yeast colonies after about 27 days of growth and increase during aging. In this respect we hypothesize to use yeast as a clock to study the onset of human aging phenotypes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 24%
Professor > Associate Professor 3 18%
Student > Master 3 18%
Student > Ph. D. Student 2 12%
Other 1 6%
Other 2 12%
Unknown 2 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 47%
Biochemistry, Genetics and Molecular Biology 6 35%
Unknown 3 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2015.
All research outputs
#17,554,426
of 25,806,080 outputs
Outputs from Frontiers in oncology
#8,011
of 22,805 outputs
Outputs of similar age
#174,311
of 252,076 outputs
Outputs of similar age from Frontiers in oncology
#68
of 162 outputs
Altmetric has tracked 25,806,080 research outputs across all sources so far. This one is in the 31st percentile – i.e., 31% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,805 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 252,076 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 162 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.