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The Tumor Microenvironment: A Pitch for Multiple Players

Overview of attention for article published in Frontiers in oncology, January 2013
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2 X users

Citations

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125 Dimensions

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136 Mendeley
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Title
The Tumor Microenvironment: A Pitch for Multiple Players
Published in
Frontiers in oncology, January 2013
DOI 10.3389/fonc.2013.00090
Pubmed ID
Authors

Giovanna Schiavoni, Lucia Gabriele, Fabrizio Mattei

Abstract

The cancer microenvironment may be conceptually regarded as a pitch where the main players are resident and non-resident cellular components, each covering a defined role and interconnected by a complex network of soluble mediators. The crosstalk between these cells and the tumor cells within this environment crucially determines the fate of tumor progression. Immune cells that infiltrate the tumor bed are transported there by blood circulation and exert a variety of effects, either counteracting or favoring tumor outgrowth. Here, we review and discuss the multiple populations composing the tumor bed, with special focus on immune cells subsets that positively or negatively dictate neoplastic progression. In this scenario, the contribution of cancer stem cells within the tumor microenvironment will also be discussed. Finally, we illustrate recent advances on new integrated approaches to investigate the tumor microenvironment in vitro.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 1%
Portugal 1 <1%
Italy 1 <1%
Australia 1 <1%
United Kingdom 1 <1%
United States 1 <1%
Unknown 129 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 19%
Researcher 25 18%
Student > Bachelor 14 10%
Student > Master 14 10%
Other 13 10%
Other 14 10%
Unknown 30 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 23%
Medicine and Dentistry 24 18%
Biochemistry, Genetics and Molecular Biology 22 16%
Immunology and Microbiology 11 8%
Veterinary Science and Veterinary Medicine 4 3%
Other 7 5%
Unknown 37 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2015.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Frontiers in oncology
#9,315
of 22,414 outputs
Outputs of similar age
#221,299
of 288,986 outputs
Outputs of similar age from Frontiers in oncology
#142
of 328 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,414 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,986 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 328 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.