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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Current Challenges in the Bioinformatics of Single Cell Genomics
|
|---|---|
| Published in |
Frontiers in oncology, January 2014
|
| DOI | 10.3389/fonc.2014.00007 |
| Pubmed ID | |
| Authors |
Luwen Ning, Geng Liu, Guibo Li, Yong Hou, Yin Tong, Jiankui He |
| Abstract |
Single cell genomics is a rapidly growing field with many new techniques emerging in the past few years. However, few bioinformatics tools specific for single cell genomics analysis are available. Single cell DNA/RNA sequencing data usually have low genome coverage and high amplification bias, which makes bioinformatics analysis challenging. Many current bioinformatics tools developed for bulk cell sequencing do not work well with single cell sequencing data. Here, we summarize current challenges in the bioinformatics analysis of single cell genomic DNA sequencing and single cell transcriptomes. These challenges include calling copy number variations, identifying mutated genes in tumor samples, reconstructing cell lineages, recovering low abundant transcripts, and improving the accuracy of quantitative analysis of transcripts. Development in single cell genomics bioinformatics analysis will promote the application of this technology to basic biology and medical research. |
X Demographics
The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 22% |
| Switzerland | 2 | 11% |
| United Kingdom | 1 | 6% |
| Hong Kong | 1 | 6% |
| France | 1 | 6% |
| India | 1 | 6% |
| Sao Tome and Principe | 1 | 6% |
| Germany | 1 | 6% |
| Unknown | 6 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 50% |
| Scientists | 8 | 44% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 240 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Sweden | 2 | <1% |
| Germany | 2 | <1% |
| Belgium | 2 | <1% |
| Ghana | 1 | <1% |
| Italy | 1 | <1% |
| Czechia | 1 | <1% |
| Saudi Arabia | 1 | <1% |
| Argentina | 1 | <1% |
| Other | 5 | 2% |
| Unknown | 221 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 58 | 24% |
| Researcher | 57 | 24% |
| Student > Master | 31 | 13% |
| Student > Bachelor | 17 | 7% |
| Other | 14 | 6% |
| Other | 43 | 18% |
| Unknown | 20 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 116 | 48% |
| Biochemistry, Genetics and Molecular Biology | 60 | 25% |
| Computer Science | 12 | 5% |
| Medicine and Dentistry | 12 | 5% |
| Immunology and Microbiology | 5 | 2% |
| Other | 13 | 5% |
| Unknown | 22 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2016.
All research outputs
#2,540,560
of 25,394,764 outputs
Outputs from Frontiers in oncology
#598
of 22,440 outputs
Outputs of similar age
#28,320
of 319,416 outputs
Outputs of similar age from Frontiers in oncology
#3
of 51 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,440 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,416 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.