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X Demographics
Mendeley readers
Attention Score in Context
| Title |
BRCA 1/2-Mutation Related and Sporadic Breast and Ovarian Cancers: More Alike than Different
|
|---|---|
| Published in |
Frontiers in oncology, January 2014
|
| DOI | 10.3389/fonc.2014.00019 |
| Pubmed ID | |
| Authors |
Melissa Burgess, Shannon Puhalla |
| Abstract |
No longer is histology solely predictive of cancer treatment and outcome. There is an increasing influence of tumor genomic characteristics on therapeutic options. Both breast and ovarian cancers are at higher risk of development in patients with BRCA 1/2-germline mutations. Recent data from The Cancer Genome Atlas and others have shown a number of genomic similarities between triple negative breast cancers (TNBCs) and ovarian cancers. Recently, poly (ADP-ribose) polymerase (PARP) inhibitors have shown promising activity in hereditary BRCA 1/2-mutated and sporadic breast and ovarian cancers. In this review, we will summarize the current literature regarding the genomic and phenotypic similarities between BRCA 1/2-mutation related cancers, sporadic TNBCs, and sporadic ovarian cancers. We will also review Phase I, II, and III data using PARP inhibitors for these malignancies and compare and contrast the results with respect to histology. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | <1% |
| Ecuador | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 131 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 27 | 20% |
| Student > Ph. D. Student | 18 | 13% |
| Student > Bachelor | 17 | 13% |
| Student > Master | 16 | 12% |
| Other | 16 | 12% |
| Other | 21 | 16% |
| Unknown | 19 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 44 | 33% |
| Agricultural and Biological Sciences | 30 | 22% |
| Biochemistry, Genetics and Molecular Biology | 24 | 18% |
| Chemistry | 4 | 3% |
| Immunology and Microbiology | 3 | 2% |
| Other | 9 | 7% |
| Unknown | 20 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2019.
All research outputs
#15,533,143
of 25,394,764 outputs
Outputs from Frontiers in oncology
#4,874
of 22,440 outputs
Outputs of similar age
#180,978
of 319,410 outputs
Outputs of similar age from Frontiers in oncology
#18
of 51 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,440 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,410 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.