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Cancer-Associated Fibroblasts as Another Polarized Cell Type of the Tumor Microenvironment

Overview of attention for article published in Frontiers in oncology, March 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (65th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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1 X user
wikipedia
2 Wikipedia pages

Citations

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372 Dimensions

Readers on

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465 Mendeley
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Title
Cancer-Associated Fibroblasts as Another Polarized Cell Type of the Tumor Microenvironment
Published in
Frontiers in oncology, March 2014
DOI 10.3389/fonc.2014.00062
Pubmed ID
Authors

Martin Augsten

Abstract

Tumor- or cancer-associated fibroblasts (CAFs) are one of the most abundant stromal cell types in different carcinomas and comprise a heterogeneous cell population. Classically, CAFs are assigned with pro-tumorigenic effects stimulating tumor growth and progression. More recent studies demonstrated also tumor-inhibitory effects of CAFs suggesting that tumor-residing fibroblasts exhibit a similar degree of plasticity as other stromal cell types. Reciprocal interactions with the tumor milieu and different sources of origin are emerging as two important factors underlying CAF heterogeneity. This review highlights recent advances in our understanding of CAF biology and proposes to expand the term of cellular "polarization," previously introduced to describe different activation states of various immune cells, onto CAFs to reflect their phenotypic diversity.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 465 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 3 <1%
Denmark 3 <1%
United States 3 <1%
Netherlands 2 <1%
United Kingdom 2 <1%
Germany 2 <1%
Saudi Arabia 1 <1%
Taiwan 1 <1%
Russia 1 <1%
Other 3 <1%
Unknown 444 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 118 25%
Student > Master 67 14%
Researcher 63 14%
Student > Bachelor 40 9%
Student > Doctoral Student 35 8%
Other 57 12%
Unknown 85 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 120 26%
Biochemistry, Genetics and Molecular Biology 95 20%
Medicine and Dentistry 81 17%
Immunology and Microbiology 23 5%
Engineering 15 3%
Other 37 8%
Unknown 94 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2018.
All research outputs
#8,595,726
of 25,998,826 outputs
Outputs from Frontiers in oncology
#3,265
of 22,783 outputs
Outputs of similar age
#79,839
of 242,260 outputs
Outputs of similar age from Frontiers in oncology
#13
of 59 outputs
Altmetric has tracked 25,998,826 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 22,783 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,260 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.