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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Oncolytic Viruses as Anticancer Vaccines
|
|---|---|
| Published in |
Frontiers in oncology, July 2014
|
| DOI | 10.3389/fonc.2014.00188 |
| Pubmed ID | |
| Authors |
Norman Woller, Engin Gürlevik, Cristina-Ileana Ureche, Anja Schumacher, Florian Kühnel |
| Abstract |
Oncolytic virotherapy has shown impressive results in preclinical studies and first promising therapeutic outcomes in clinical trials as well. Since viruses are known for a long time as excellent vaccination agents, oncolytic viruses are now designed as novel anticancer agents combining the aspect of lysis-dependent cytoreductive activity with concomitant induction of antitumoral immune responses. Antitumoral immune activation by oncolytic virus infection of tumor tissue comprises both, immediate effects of innate immunity and also adaptive responses for long lasting antitumoral activity, which is regarded as the most prominent challenge in clinical oncology. To date, the complex effects of a viral tumor infection on the tumor microenvironment and the consequences for the tumor-infiltrating immune cell compartment are poorly understood. However, there is more and more evidence that a tumor infection by an oncolytic virus opens up a number of options for further immunomodulating interventions such as systemic chemotherapy, generic immunostimulating strategies, dendritic cell-based vaccines, and antigenic libraries to further support clinical efficacy of oncolytic virotherapy. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 9% |
| Spain | 1 | 9% |
| Paraguay | 1 | 9% |
| Mexico | 1 | 9% |
| United Kingdom | 1 | 9% |
| Unknown | 6 | 55% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 91% |
| Science communicators (journalists, bloggers, editors) | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | <1% |
| Malaysia | 1 | <1% |
| Netherlands | 1 | <1% |
| Austria | 1 | <1% |
| Australia | 1 | <1% |
| Canada | 1 | <1% |
| Denmark | 1 | <1% |
| Russia | 1 | <1% |
| Unknown | 129 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 33 | 24% |
| Student > Ph. D. Student | 27 | 20% |
| Student > Master | 24 | 18% |
| Researcher | 19 | 14% |
| Student > Doctoral Student | 9 | 7% |
| Other | 12 | 9% |
| Unknown | 13 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 31% |
| Biochemistry, Genetics and Molecular Biology | 27 | 20% |
| Medicine and Dentistry | 18 | 13% |
| Immunology and Microbiology | 18 | 13% |
| Chemistry | 6 | 4% |
| Other | 11 | 8% |
| Unknown | 15 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2024.
All research outputs
#1,656,978
of 25,746,891 outputs
Outputs from Frontiers in oncology
#308
of 22,775 outputs
Outputs of similar age
#16,033
of 240,375 outputs
Outputs of similar age from Frontiers in oncology
#2
of 95 outputs
Altmetric has tracked 25,746,891 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,775 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,375 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.