Title |
A Multicenter Pilot Study Examining the Role of Circulating Tumor Cells as a Blood-Based Tumor Marker in Patients with Extensive Small-Cell Lung Cancer
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Published in |
Frontiers in oncology, October 2014
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DOI | 10.3389/fonc.2014.00271 |
Pubmed ID | |
Authors |
Chao H. Huang, Jo A. Wick, Gurusingham Sitta Sittampalam, Victor Sanjit Nirmalanandhan, Apar Kishor Ganti, Prakash C. Neupane, Stephen K. Williamson, Andrew K. Godwin, Sarah Schmitt, Nora J. Smart, Sarah Spencer, Peter J. Van Veldhuizen |
Abstract |
Small-cell lung cancer (SCLC), a variant of lung cancer marked by early metastases, accounts for 13% of all lung cancers diagnosed in US. Despite high response rates to treatment, it is an aggressive disease with a median survival of 9-11 months for patients with extensive stage (EX-SCLC). Detection of circulating tumor cells (CTCs) is a novel laboratory technique currently in use to determine response to therapy and to predict prognosis in breast, colorectal, and prostate cancer. We initiated a pilot study to analyze the role of CTCs as a biomarker of response and relapse in patients with EX-SCLC. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Australia | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 6 | 19% |
Student > Ph. D. Student | 4 | 13% |
Student > Doctoral Student | 3 | 10% |
Professor | 3 | 10% |
Researcher | 3 | 10% |
Other | 4 | 13% |
Unknown | 8 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 42% |
Agricultural and Biological Sciences | 3 | 10% |
Engineering | 2 | 6% |
Computer Science | 1 | 3% |
Unspecified | 1 | 3% |
Other | 2 | 6% |
Unknown | 9 | 29% |