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Altered Transcriptional Control Networks with Trans-Differentiation of Isogenic Mutant-KRas NSCLC Models

Overview of attention for article published in Frontiers in oncology, December 2014
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Title
Altered Transcriptional Control Networks with Trans-Differentiation of Isogenic Mutant-KRas NSCLC Models
Published in
Frontiers in oncology, December 2014
DOI 10.3389/fonc.2014.00344
Pubmed ID
Authors

John A. Haley, Elizabeth Haughney, Erica Ullman, James Bean, John D. Haley, Marc Y. Fink

Abstract

The capacity of cancer cells to undergo epithelial mesenchymal trans-differentiation has been implicated as a factor driving metastasis, through the acquisition of enhanced migratory/invasive cell programs and the engagement of anti-apoptotic mechanisms promoting drug and radiation resistance. Our aim was to define molecular signaling changes associated with mesenchymal trans-differentiation in two KRas mutant NSCLC models. We focused on central transcription and epigenetic regulators predicted to be important for mesenchymal cell survival.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 29%
Student > Bachelor 6 21%
Student > Master 4 14%
Student > Doctoral Student 1 4%
Other 1 4%
Other 3 11%
Unknown 5 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 29%
Agricultural and Biological Sciences 8 29%
Engineering 2 7%
Physics and Astronomy 1 4%
Computer Science 1 4%
Other 2 7%
Unknown 6 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2015.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Frontiers in oncology
#9,315
of 22,414 outputs
Outputs of similar age
#258,999
of 368,077 outputs
Outputs of similar age from Frontiers in oncology
#57
of 94 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,414 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 368,077 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 94 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.