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The Emerging Role of Exosomes in Epithelial–Mesenchymal-Transition in Cancer

Overview of attention for article published in Frontiers in oncology, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
twitter
2 X users
facebook
1 Facebook page

Citations

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119 Dimensions

Readers on

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186 Mendeley
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Title
The Emerging Role of Exosomes in Epithelial–Mesenchymal-Transition in Cancer
Published in
Frontiers in oncology, December 2014
DOI 10.3389/fonc.2014.00361
Pubmed ID
Authors

Laura Jayne Vella

Abstract

Metastasis in cancer consists of multiple steps, including epithelial-mesenchymal-transition (EMT), which is characterized by the loss of epithelial-like characteristics and the gain of mesenchymal-like attributes including cell migration and invasion. It is clear that the tumor microenvironment can promote the metastatic cascade and that intercellular communication is necessary for this to occur. Exosomes are small membranous vesicles secreted by most cell types into the extracellular environment and they are important communicators in the tumor microenvironment. They promote angiogenesis, invasion, and proliferation in recipient cells to support tumor growth and a prometastatic phenotype. Although it is clear that exosomes contribute to cancer cell plasticity, experimental evidence to define exosome induced plasticity as EMT is only just coming to light. This review will discuss recent research on exosomal regulation of the EMT process in the tumor microenvironment.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 186 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Chile 1 <1%
France 1 <1%
Korea, Republic of 1 <1%
Mexico 1 <1%
Belgium 1 <1%
Unknown 180 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 44 24%
Researcher 33 18%
Student > Master 30 16%
Student > Bachelor 19 10%
Student > Doctoral Student 12 6%
Other 21 11%
Unknown 27 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 56 30%
Agricultural and Biological Sciences 43 23%
Medicine and Dentistry 25 13%
Engineering 10 5%
Pharmacology, Toxicology and Pharmaceutical Science 4 2%
Other 16 9%
Unknown 32 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2023.
All research outputs
#3,415,510
of 25,374,917 outputs
Outputs from Frontiers in oncology
#1,073
of 22,416 outputs
Outputs of similar age
#45,360
of 360,182 outputs
Outputs of similar age from Frontiers in oncology
#7
of 96 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,416 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,182 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.