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CTLA-4 and PD-1 Pathway Blockade: Combinations in the Clinic

Overview of attention for article published in Frontiers in oncology, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

twitter
7 X users
patent
1 patent
googleplus
1 Google+ user

Citations

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200 Dimensions

Readers on

mendeley
224 Mendeley
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Title
CTLA-4 and PD-1 Pathway Blockade: Combinations in the Clinic
Published in
Frontiers in oncology, January 2015
DOI 10.3389/fonc.2014.00385
Pubmed ID
Authors

Margaret K. Callahan, Michael A. Postow, Jedd D. Wolchok

Abstract

Checkpoint blocking antibodies targeting regulatory molecules on T cells such as CTLA-4 and PD-1 have reinvigorated the field of cancer immunotherapy. These agents have demonstrated clinical activity across a variety of tumor types. Now that safety and clinical activity has been demonstrated in the monotherapy setting, the field is moving in the direction of testing novel combinations.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 224 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Australia 1 <1%
India 1 <1%
France 1 <1%
Russia 1 <1%
Belgium 1 <1%
Japan 1 <1%
Spain 1 <1%
Unknown 215 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 54 24%
Student > Ph. D. Student 36 16%
Student > Master 34 15%
Student > Bachelor 24 11%
Other 13 6%
Other 32 14%
Unknown 31 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 51 23%
Medicine and Dentistry 43 19%
Biochemistry, Genetics and Molecular Biology 38 17%
Immunology and Microbiology 25 11%
Engineering 7 3%
Other 21 9%
Unknown 39 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2019.
All research outputs
#4,810,255
of 25,576,801 outputs
Outputs from Frontiers in oncology
#1,670
of 22,703 outputs
Outputs of similar age
#64,743
of 378,537 outputs
Outputs of similar age from Frontiers in oncology
#17
of 99 outputs
Altmetric has tracked 25,576,801 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,703 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 378,537 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 99 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.