Title |
Clinical Impact of the Immunome in Lymphoid Malignancies: The Role of Myeloid-Derived Suppressor Cells
|
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Published in |
Frontiers in oncology, May 2015
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DOI | 10.3389/fonc.2015.00104 |
Pubmed ID | |
Authors |
Calogero Vetro, Alessandra Romano, Flavia Ancora, Francesco Coppolino, Maria V. Brundo, Salvatore A. Raccuia, Fabrizio Puglisi, Daniele Tibullo, Piera La Cava, Cesarina Giallongo, Nunziatina L. Parrinello |
Abstract |
The better definition of the mutual sustainment between neoplastic cells and immune system has been translated from the bench to the bedside acquiring value as prognostic factor. Additionally, it represents a promising tool for improving therapeutic strategies. In this context, myeloid-derived suppressor cells (MDSCs) have gained a central role in tumor developing with consequent therapeutic implications. In this review, we will focus on the biological and clinical impact of the study of MDSCs in the settings of lymphoid malignancies. |
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Mendeley readers
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