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Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers

Overview of attention for article published in Frontiers in oncology, June 2015
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36 Mendeley
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Title
Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers
Published in
Frontiers in oncology, June 2015
DOI 10.3389/fonc.2015.00140
Pubmed ID
Authors

Robert Clarke, Katherine L. Cook

Abstract

The unfolded protein response (UPR) is an ancient stress response that enables a cell to manage the energetic stress that accompanies protein folding. There has been a significant recent increase in our understanding of the UPR, how it integrates physiological processes within cells, and how this integration can affect cancer cells and cell fate decisions. Recent publications have highlighted the role of UPR signaling components on mediating various cell survival pathways, cellular metabolism and bioenergenics, and autophagy. We address the role of UPR on mediating endocrine therapy resistance and estrogen receptor-positive breast cancer cell survival.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 22%
Researcher 5 14%
Student > Master 5 14%
Student > Bachelor 4 11%
Student > Postgraduate 3 8%
Other 9 25%
Unknown 2 6%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 31%
Agricultural and Biological Sciences 9 25%
Medicine and Dentistry 6 17%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Mathematics 1 3%
Other 4 11%
Unknown 4 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2015.
All research outputs
#17,286,645
of 25,374,917 outputs
Outputs from Frontiers in oncology
#8,025
of 22,416 outputs
Outputs of similar age
#165,642
of 278,313 outputs
Outputs of similar age from Frontiers in oncology
#38
of 76 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,416 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,313 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.