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Harnessing Pandemonium: The Clinical Implications of Tumor Heterogeneity in Ovarian Cancer

Overview of attention for article published in Frontiers in oncology, June 2015
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3 X users

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60 Mendeley
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Title
Harnessing Pandemonium: The Clinical Implications of Tumor Heterogeneity in Ovarian Cancer
Published in
Frontiers in oncology, June 2015
DOI 10.3389/fonc.2015.00149
Pubmed ID
Authors

Sarah P. Blagden

Abstract

Heterogeneity has emerged as a key feature of ovarian cancer between different ovarian cancer subtypes; within single ovarian cancer subtypes; and within individual patient tumors. At the genomic level, with the advent of ultra-deep sequencing technologies alongside RNA-Seq, epigenomics, and proteomics, the complexity surrounding heterogeneity has deepened. Here, we summarize the emerging understanding of heterogeneity in cancer as a whole and the key discoveries in this area relating to ovarian cancer. We explore the therapeutic limitations and possibilities posed by heterogeneity and how these will influence the future of ovarian cancer treatment and research.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Unknown 59 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 25%
Researcher 8 13%
Student > Bachelor 5 8%
Student > Master 5 8%
Other 3 5%
Other 9 15%
Unknown 15 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 23%
Medicine and Dentistry 11 18%
Agricultural and Biological Sciences 9 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Chemistry 2 3%
Other 5 8%
Unknown 17 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2015.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from Frontiers in oncology
#8,025
of 22,416 outputs
Outputs of similar age
#165,143
of 277,323 outputs
Outputs of similar age from Frontiers in oncology
#38
of 71 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,416 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,323 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 71 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.