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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Targeting ECM Disrupts Cancer Progression
|
|---|---|
| Published in |
Frontiers in oncology, October 2015
|
| DOI | 10.3389/fonc.2015.00224 |
| Pubmed ID | |
| Authors |
Freja A. Venning, Lena Wullkopf, Janine T. Erler |
| Abstract |
Metastatic complications are responsible for more than 90% of cancer-related deaths. The progression from an isolated tumor to disseminated metastatic disease is a multistep process, with each step involving intricate cross talk between the cancer cells and their non-cellular surroundings, the extracellular matrix (ECM). Many ECM proteins are significantly deregulated during the progression of cancer, causing both biochemical and biomechanical changes that together promote the metastatic cascade. In this review, the influence of several ECM proteins on these multiple steps of cancer spread is summarized. In addition, we highlight the promising (pre-)clinical data showing benefits of targeting these ECM macromolecules to prevent cancer progression. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 50% |
| Switzerland | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 310 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 305 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 86 | 28% |
| Researcher | 47 | 15% |
| Student > Master | 43 | 14% |
| Student > Bachelor | 24 | 8% |
| Student > Doctoral Student | 18 | 6% |
| Other | 29 | 9% |
| Unknown | 63 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 76 | 25% |
| Agricultural and Biological Sciences | 56 | 18% |
| Medicine and Dentistry | 25 | 8% |
| Engineering | 25 | 8% |
| Immunology and Microbiology | 15 | 5% |
| Other | 45 | 15% |
| Unknown | 68 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2017.
All research outputs
#8,534,976
of 25,374,647 outputs
Outputs from Frontiers in oncology
#3,352
of 22,416 outputs
Outputs of similar age
#100,896
of 294,426 outputs
Outputs of similar age from Frontiers in oncology
#16
of 70 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,416 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 294,426 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.