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The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling

Overview of attention for article published in Frontiers in oncology, October 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

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2 X users
wikipedia
1 Wikipedia page

Citations

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236 Dimensions

Readers on

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367 Mendeley
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Title
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling
Published in
Frontiers in oncology, October 2015
DOI 10.3389/fonc.2015.00225
Pubmed ID
Authors

Veronica Krenn, Andrea Musacchio

Abstract

Aurora B, a member of the Aurora family of serine/threonine protein kinases, is a key player in chromosome segregation. As part of a macromolecular complex known as the chromosome passenger complex, Aurora B concentrates early during mitosis in the proximity of centromeres and kinetochores, the sites of attachment of chromosomes to spindle microtubules. There, it contributes to a number of processes that impart fidelity to cell division, including kinetochore stabilization, kinetochore-microtubule attachment, and the regulation of a surveillance mechanism named the spindle assembly checkpoint. In the regulation of these processes, Aurora B is the fulcrum of a remarkably complex network of interactions that feed back on its localization and activation state. In this review, we discuss the multiple roles of Aurora B during mitosis, focusing in particular on its role at centromeres and kinetochores. Many details of the network of interactions at these locations remain poorly understood, and we focus here on several crucial outstanding questions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 367 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Netherlands 1 <1%
United States 1 <1%
Unknown 364 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 111 30%
Student > Master 43 12%
Student > Bachelor 43 12%
Researcher 38 10%
Student > Doctoral Student 22 6%
Other 26 7%
Unknown 84 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 156 43%
Agricultural and Biological Sciences 85 23%
Medicine and Dentistry 9 2%
Pharmacology, Toxicology and Pharmaceutical Science 6 2%
Chemistry 5 1%
Other 17 5%
Unknown 89 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 March 2017.
All research outputs
#7,779,140
of 25,374,917 outputs
Outputs from Frontiers in oncology
#2,722
of 22,420 outputs
Outputs of similar age
#88,715
of 292,363 outputs
Outputs of similar age from Frontiers in oncology
#10
of 68 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 22,420 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 292,363 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 68 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.