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Glycosylated Notch and Cancer

Overview of attention for article published in Frontiers in oncology, February 2016
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  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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Citations

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26 Dimensions

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45 Mendeley
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Title
Glycosylated Notch and Cancer
Published in
Frontiers in oncology, February 2016
DOI 10.3389/fonc.2016.00037
Pubmed ID
Authors

Shanmugasundaram Pakkiriswami, Africa Couto, Usha Nagarajan, Marios Georgiou

Abstract

Glycosylation is one of the key components influencing several signaling pathways implicated in cell survival and growth. The Notch signaling pathway plays a pivotal role in numerous cell fate specifications during metazoan development. Both Notch and its ligands are repeatedly glycosylated by the addition of sugar moieties, such as O-fucose, O-glucose, or O-xylose, to bring about structural and functional changes. Disruption to glycosylation processes of Notch proteins result in developmental disorders and disease, including cancer. This review summarizes the importance and recent updates on the role of glycosylated Notch proteins in tumorigenesis and tumor metastasis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 2%
Taiwan 1 2%
Brazil 1 2%
Unknown 42 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 27%
Researcher 9 20%
Student > Bachelor 6 13%
Student > Master 6 13%
Student > Postgraduate 2 4%
Other 4 9%
Unknown 6 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 20 44%
Agricultural and Biological Sciences 9 20%
Engineering 2 4%
Immunology and Microbiology 2 4%
Business, Management and Accounting 1 2%
Other 3 7%
Unknown 8 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2016.
All research outputs
#15,879,822
of 25,584,565 outputs
Outputs from Frontiers in oncology
#5,029
of 22,718 outputs
Outputs of similar age
#163,357
of 312,500 outputs
Outputs of similar age from Frontiers in oncology
#35
of 90 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,718 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,500 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.