Title |
Apparatus for Histological Validation of In Vivo and Ex Vivo Magnetic Resonance Imaging of the Human Prostate
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Published in |
Frontiers in oncology, March 2017
|
DOI | 10.3389/fonc.2017.00047 |
Pubmed ID | |
Authors |
Roger M. Bourne, Colleen Bailey, Edward William Johnston, Hayley Pye, Susan Heavey, Hayley Whitaker, Bernard Siow, Alex Freeman, Greg L. Shaw, Ashwin Sridhar, Thomy Mertzanidou, David J. Hawkes, Daniel C. Alexander, Shonit Punwani, Eleftheria Panagiotaki |
Abstract |
This article describes apparatus to aid histological validation of magnetic resonance imaging studies of the human prostate. The apparatus includes a 3D-printed patient-specific mold that facilitates aligned in vivo and ex vivo imaging, in situ tissue fixation, and tissue sectioning with minimal organ deformation. The mold and a dedicated container include MRI-visible landmarks to enable consistent tissue positioning and minimize image registration complexity. The inclusion of high spatial resolution ex vivo imaging aids in registration of in vivo MRI and histopathology data. |
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Geographical breakdown
Country | Count | As % |
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United Kingdom | 4 | 33% |
United States | 2 | 17% |
Australia | 1 | 8% |
Switzerland | 1 | 8% |
Unknown | 4 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 9 | 75% |
Scientists | 2 | 17% |
Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 68 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 16 | 24% |
Student > Ph. D. Student | 11 | 16% |
Student > Master | 6 | 9% |
Professor > Associate Professor | 4 | 6% |
Other | 4 | 6% |
Other | 13 | 19% |
Unknown | 14 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 21% |
Engineering | 9 | 13% |
Computer Science | 5 | 7% |
Physics and Astronomy | 5 | 7% |
Agricultural and Biological Sciences | 3 | 4% |
Other | 12 | 18% |
Unknown | 20 | 29% |