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The Unfolded Protein Response: At the Intersection between Endoplasmic Reticulum Function and Mitochondrial Bioenergetics

Overview of attention for article published in Frontiers in oncology, April 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
11 X users

Citations

dimensions_citation
41 Dimensions

Readers on

mendeley
77 Mendeley
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Title
The Unfolded Protein Response: At the Intersection between Endoplasmic Reticulum Function and Mitochondrial Bioenergetics
Published in
Frontiers in oncology, April 2017
DOI 10.3389/fonc.2017.00055
Pubmed ID
Authors

Amado Carreras-Sureda, Philippe Pihán, Claudio Hetz

Abstract

Endoplasmic reticulum (ER) to mitochondria communication has emerged in recent years as a signaling hub regulating cellular physiology with a relevant contribution to diseases including cancer and neurodegeneration. This functional integration is exerted through discrete interorganelle structures known as mitochondria-associated membranes (MAMs). At these domains, ER/mitochondria physically associate to dynamically adjust metabolic demands and the response to stress stimuli. Here, we provide a focused overview of how the ER shapes the function of the mitochondria, giving a special emphasis to the significance of local signaling of the unfolded protein response at MAMs. The implications to cell fate control and the progression of cancer are also discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Finland 1 1%
Unknown 76 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 18%
Student > Ph. D. Student 13 17%
Student > Master 11 14%
Student > Bachelor 7 9%
Student > Doctoral Student 6 8%
Other 12 16%
Unknown 14 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 30 39%
Agricultural and Biological Sciences 10 13%
Neuroscience 7 9%
Medicine and Dentistry 5 6%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Other 6 8%
Unknown 15 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2017.
All research outputs
#1,798,517
of 25,382,440 outputs
Outputs from Frontiers in oncology
#360
of 22,428 outputs
Outputs of similar age
#34,186
of 323,671 outputs
Outputs of similar age from Frontiers in oncology
#7
of 74 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,428 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,671 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.