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Platelet Metabolism and Other Targeted Drugs; Potential Impact on Immunotherapy

Overview of attention for article published in Frontiers in oncology, April 2018
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Title
Platelet Metabolism and Other Targeted Drugs; Potential Impact on Immunotherapy
Published in
Frontiers in oncology, April 2018
DOI 10.3389/fonc.2018.00107
Pubmed ID
Authors

Preeti Kanikarla-Marie, Michael Lam, Alexey V. Sorokin, Michael J. Overman, Scott Kopetz, David G. Menter

Abstract

The role of platelets in cancer progression has been well recognized in the field of cancer biology. Emerging studies are elaborating further the additional roles and added extent that platelets play in promoting tumorigenesis. Platelets release factors that support tumor growth and also form heterotypic aggregates with tumor cells, which can provide an immune-evasive advantage. Their most critical role may be the inhibition of immune cell function that can negatively impact the body's ability in preventing tumor establishment and growth. This review summarizes the importance of platelets in tumor progression, therapeutic response, survival, and finally the notion of immunotherapy modulation being likely to benefit from the inclusion of platelet inhibitors.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 21%
Student > Ph. D. Student 5 13%
Student > Bachelor 4 11%
Student > Master 4 11%
Professor > Associate Professor 2 5%
Other 4 11%
Unknown 11 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 16%
Medicine and Dentistry 6 16%
Agricultural and Biological Sciences 3 8%
Engineering 2 5%
Nursing and Health Professions 1 3%
Other 6 16%
Unknown 14 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2018.
All research outputs
#22,905,350
of 25,540,105 outputs
Outputs from Frontiers in oncology
#16,130
of 22,658 outputs
Outputs of similar age
#300,741
of 340,917 outputs
Outputs of similar age from Frontiers in oncology
#114
of 147 outputs
Altmetric has tracked 25,540,105 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,658 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,917 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 147 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.