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Regulation of Malignant Hematopoiesis by Bone Marrow Microenvironment

Overview of attention for article published in Frontiers in oncology, April 2018
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Title
Regulation of Malignant Hematopoiesis by Bone Marrow Microenvironment
Published in
Frontiers in oncology, April 2018
DOI 10.3389/fonc.2018.00119
Pubmed ID
Authors

Noboru Asada

Abstract

Hematopoietic stem cells (HSCs) that give rise to all kinds of hematopoietic lineage cells on various demands throughout life are maintained in a specialized microenvironment called "niche" in the bone marrow (BM). Defining niche cells and unveiling its function have been the subject of intense study, and it is becoming increasingly clear how niche cells regulate HSCs in normal hematopoiesis. Leukemia stem cells (LSCs), which are able to produce leukemic cells and maintain leukemic clones, are assumed to share common features with healthy HSCs. Accumulating evidence suggests that LSCs reside in a specialized BM microenvironment; moreover, LSCs could control and rebuild the microenvironment to enhance their progression and survival. This article discusses the recent advances in our knowledge of the microenvironment supporting malignant hematopoiesis, including LSC niche.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 53 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 19%
Student > Ph. D. Student 10 19%
Researcher 6 11%
Student > Master 5 9%
Other 2 4%
Other 4 8%
Unknown 16 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 28%
Medicine and Dentistry 6 11%
Agricultural and Biological Sciences 6 11%
Immunology and Microbiology 2 4%
Unspecified 1 2%
Other 2 4%
Unknown 21 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2018.
All research outputs
#19,951,180
of 25,382,440 outputs
Outputs from Frontiers in oncology
#9,328
of 22,428 outputs
Outputs of similar age
#250,069
of 340,059 outputs
Outputs of similar age from Frontiers in oncology
#88
of 149 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,428 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,059 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 149 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.