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Urinary Lead Concentration Is an Independent Predictor of Cancer Mortality in the U.S. General Population

Overview of attention for article published in Frontiers in oncology, June 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

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1 news outlet
twitter
6 X users

Citations

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18 Dimensions

Readers on

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26 Mendeley
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Title
Urinary Lead Concentration Is an Independent Predictor of Cancer Mortality in the U.S. General Population
Published in
Frontiers in oncology, June 2018
DOI 10.3389/fonc.2018.00242
Pubmed ID
Authors

Sen Li, Jiaxin Wang, Biao Zhang, Yuan Liu, Tao Lu, Yuanyuan Shi, Guangliang Shan, Ling Dong

Abstract

Lead is a ubiquitous pollutant that constitutes an environmental hazard worldwide. Although lead has been known as a carcinogenic factor in animal models, its role in human carcinogenesis is still a topic of debate with limited epidemiological evidence. Moreover, the association between urinary lead, as the most non-invasive and accessible way for lead measurement in human, and cancer mortality in general population has never been explored. We addressed this subject using continuous National Health and Nutrition Examination Survey 1999-2010 data and its Mortality Follow-Up Study. Of 5,316 subjects in study population, 161 participants died due to cancer. Cancer-specific mortality was associated with urinary lead levels after multivariable adjustment. Kaplan-Meier survival curve and cubic regression spline analyses indicated that high concentration of urinary lead exhibited significant association with raised death rate of cancer. Despite the marked decrease in environmental lead levels over the past three decades, lead exposure is still the significant determinant of cancer mortality in general population in U.S., and quantification of urinary lead may serve as a non-invasive approach to facilitate biomarker discovery and clinical translational research.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 15%
Researcher 4 15%
Other 2 8%
Student > Bachelor 2 8%
Professor 2 8%
Other 3 12%
Unknown 9 35%
Readers by discipline Count As %
Environmental Science 4 15%
Medicine and Dentistry 4 15%
Pharmacology, Toxicology and Pharmaceutical Science 3 12%
Unspecified 1 4%
Agricultural and Biological Sciences 1 4%
Other 3 12%
Unknown 10 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2021.
All research outputs
#2,640,512
of 25,385,509 outputs
Outputs from Frontiers in oncology
#641
of 22,428 outputs
Outputs of similar age
#52,644
of 343,092 outputs
Outputs of similar age from Frontiers in oncology
#12
of 152 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,428 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,092 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 152 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.