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The Future Is Now—Prospective Study of Radiosurgery for More Than 4 Brain Metastases to Start in 2018!

Overview of attention for article published in Frontiers in oncology, September 2018
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  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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Title
The Future Is Now—Prospective Study of Radiosurgery for More Than 4 Brain Metastases to Start in 2018!
Published in
Frontiers in oncology, September 2018
DOI 10.3389/fonc.2018.00380
Pubmed ID
Authors

David Roberge, Paul D. Brown, Anthony Whitton, Chris O'Callaghan, Anne Leis, Jeffrey Greenspoon, Grace Li Smith, Jennifer J. Hu, Alan Nichol, Chad Winch, Michael D. Chan

Abstract

Stereotactic radiosurgery (SRS) has replaced whole brain radiotherapy (WBRT) as standard therapy for most patients with four or fewer brain metastases due to improved cognitive outcomes and more favorable health related quality of life (QoL). Whether SRS or WBRT is the optimal radiation modality for patients with five to fifteen brain metastases remains an open question. Efforts are underway to develop prospective evidence to answer this question. One of the planned trials is a Canadian Cancer Trials Group (CCTG)-lead North American intergroup trial. In general cancer treatments must have two basic aims: prolonging and improving QoL. In this vein, the selection of overall survival and QoL metrics as outcomes appear obvious. Potential secondary outcomes are numerous: patient/disease related, treatment related, economic, translational, imaging, and dosimetric. In designing a trial, one must also ponder what is standard WBRT-specifically, whether it should be associated with memantine. With the rapid accrual of an intergroup trial of hippocampal-sparing WBRT, we may find that the standard WBRT regimen changes in the course of planned trials. As up-front radiosurgery is increasingly used for more than 4 brain metastases without high level evidence, we have a window of opportunity to develop high quality evidence which will help guide our future clinical and policy decisions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 17%
Researcher 6 15%
Other 4 10%
Student > Postgraduate 4 10%
Student > Bachelor 3 7%
Other 9 22%
Unknown 8 20%
Readers by discipline Count As %
Medicine and Dentistry 14 34%
Unspecified 3 7%
Neuroscience 3 7%
Chemistry 2 5%
Psychology 2 5%
Other 4 10%
Unknown 13 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 October 2018.
All research outputs
#16,053,755
of 25,385,509 outputs
Outputs from Frontiers in oncology
#5,640
of 22,432 outputs
Outputs of similar age
#200,314
of 347,952 outputs
Outputs of similar age from Frontiers in oncology
#76
of 185 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,432 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 347,952 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 185 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.