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Case Report: B Lymphocyte Disorders Under COVID-19 Inflammatory Pressure

Overview of attention for article published in Frontiers in oncology, January 2021
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  • Good Attention Score compared to outputs of the same age and source (75th percentile)

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Title
Case Report: B Lymphocyte Disorders Under COVID-19 Inflammatory Pressure
Published in
Frontiers in oncology, January 2021
DOI 10.3389/fonc.2020.582901
Pubmed ID
Authors

Gloria Taliani, Elena Follini, Lorenzo Guglielmetti, Patrizia Bernuzzi, Alberto Faggi, Patrizia Ferrante, Elisa Fronti, Laura Gerna, Maria Cristina Leoni, Franco Paolillo, Giovanna Ratti, Alessandro Ruggieri, Caterina Valdatta, Alessandra Donisi, Adriano Zangrandi, Lara Pochintesta, Carlo Moroni, Daria Sacchini, Daniele Vallisa, Mauro Codeluppi, the COVID-Piacenza Group, Daniela Aschieri, Mario Barbera, Carlo Cagnoni, Luigi Cavanna, Cosimo Franco, Chiara Gorrini, Andrea Magnacavallo, Massimo Nolli, Massimo Piepoli, Roberta Schiavo, Matteo Silva, Marco Stabile, Angela Rossi, Giovanni Vadacca

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects humans through the angiotensin converting enzyme-2 (ACE-2) receptor expressed on many cells, including lymphocytes. In Covid-19 patients IL-6 is overexpressed, and hyperactivated plasmacytoid lymphocytes are detected in peripheral blood film. We hypothesize that, due to the unpredictable interaction between the new virus and the B cell lineage of infected patients, a cascade of out of control events can ensue, capable of determining unexpected pathologic disorders involving such lineage. Here we report two cases of autoimmune hemolytic anemia (AIHA) and two cases of B-cell hematological malignancies developed or reactivated during acute SARS-CoV-2 infection. The temporal relationship of the events may suggest a potential causal relationship between SARS-CoV-2 infection and the hematopoietic disorders. We suggest that special attention should be paid to COVID-19 patients with underlining B cell lineage disorders.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 10%
Student > Doctoral Student 4 10%
Student > Master 4 10%
Student > Postgraduate 4 10%
Student > Ph. D. Student 3 8%
Other 4 10%
Unknown 17 43%
Readers by discipline Count As %
Medicine and Dentistry 11 28%
Agricultural and Biological Sciences 3 8%
Nursing and Health Professions 2 5%
Business, Management and Accounting 1 3%
Chemical Engineering 1 3%
Other 2 5%
Unknown 20 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2023.
All research outputs
#14,987,556
of 25,483,400 outputs
Outputs from Frontiers in oncology
#4,173
of 22,577 outputs
Outputs of similar age
#260,573
of 526,664 outputs
Outputs of similar age from Frontiers in oncology
#183
of 780 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,577 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 526,664 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 780 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.